Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis

Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis

Highlights NGAL is expressed by inflammatory infiltrates and active VICs in the stenotic AV, being predominantly associated to inflammation, osteogenesis, and calcification. The levels of NGAL are higher in VICs and AVs from men than women’s and are associated with pathological features of AS. Intra...

Full description

Bibliographic Details
Main Authors: Eva Jover, Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Amaya Fernández-Celis, Alicia Gainza, Vanessa Arrieta, Amaia García-Peña, Virginia Álvarez, Rafael Sádaba, Frederic Jaisser, Natalia López-Andrés
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Biology of Sex Differences
Subjects:
Aortic stenosis
Sex
Valve interstitial cells
NGAL
Valvular heart disease
Calcification
Online Access:https://doi.org/10.1186/s13293-022-00480-w

Similar Items

Similar Items