Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients
Patients with profound bilateral deafness (BD) are prone to suffering from tinnitus, which further leads to psychological comorbidities and makes it more difficult for patients to communicate with people. This study was aimed at investigating the effect of cochlear implants (CIs) on tinnitus distres...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2021-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2021/6678863 |
| _version_ | 1826998732282920960 |
|---|---|
| author | Juanmei Yang Jing Song Xiang Zhao Carol Pang Ning Cong Zhao Han |
| author_facet | Juanmei Yang Jing Song Xiang Zhao Carol Pang Ning Cong Zhao Han |
| author_sort | Juanmei Yang |
| collection | DOAJ |
| description | Patients with profound bilateral deafness (BD) are prone to suffering from tinnitus, which further leads to psychological comorbidities and makes it more difficult for patients to communicate with people. This study was aimed at investigating the effect of cochlear implants (CIs) on tinnitus distress and psychological comorbidities in patients with profound BD. This multicenter retrospective study reviewed 51 patients with severe postlingual BD who underwent cochlear implantation; 49 patients underwent unilateral cochlear implantation, and 2 patients underwent bilateral cochlear implantation. The patients were asked to complete all the questionnaires, including the tinnitus handicap inventory (THI), the visual analog scale (VAS) score, the Hospital Anxiety and Depression Scale Questionnaire (HADS), the Categories of Auditory Performance (CAP), and the Speech Intelligibility Rating (SIR), at least 4 months after implantation when the CI was on or off, in approximately May-June 2019. In our study, 94% (48/51) of BD patients suffered from tinnitus before CI, and 77% (37/48) of them suffered from bilateral tinnitus. In addition, 50.9% (26/51) of the CI patients were suffering from anxiety, 52.9% (27/51) of them were suffering from depression (score≥8), and 66.7% (34/51) (27/51) of them were suffering from anxiety or depression. Cochlear implantation could reduce tinnitus more obviously when the CI was on than when the CI was off. Cochlear implantation also reduced anxiety/depression severity. There were significantly positive correlations between tinnitus severity and anxiety/depression severity before and after surgery. Moreover, hearing improvement is positively correlated with reduction level of tinnitus, the better hearing, and the lesser severity of tinnitus. Thus, along with effective restoration of deafferentation, cochlear implantation shows positive therapeutic effects on tinnitus and psychological comorbidities, providing a reference for future clinical and research work. |
| first_indexed | 2024-04-11T20:01:39Z |
| format | Article |
| id | doaj.art-cb145f41994944e4b596691c0339a5eb |
| institution | Directory Open Access Journal |
| issn | 2090-5904 1687-5443 |
| language | English |
| last_indexed | 2025-02-18T10:18:51Z |
| publishDate | 2021-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj.art-cb145f41994944e4b596691c0339a5eb2024-11-02T05:31:46ZengHindawi LimitedNeural Plasticity2090-59041687-54432021-01-01202110.1155/2021/66788636678863Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant PatientsJuanmei Yang0Jing Song1Xiang Zhao2Carol Pang3Ning Cong4Zhao Han5Department of Otology and Skull Base Surgery, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai 200031, ChinaDepartment of Otology and Skull Base Surgery, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai 200031, ChinaDepartment of Traditional Chinese Medicine, Shandong Zaozhuang Municipal Hospital, Shandong Zaozhuang 277100, ChinaAudiology, Speech & Medical Research Institute, Nurotron Biotechnology Co., Ltd, Hangzhou 310011, ChinaShanghai Clinical Medical Center of Hearing Medicine, Shanghai 200031, ChinaDepartment of Otorhinolaryngology, Huadong Hospital Affiliated with Fudan University, 200040, No. 221 West Yan’an Road, Jing An District, Shanghai, ChinaPatients with profound bilateral deafness (BD) are prone to suffering from tinnitus, which further leads to psychological comorbidities and makes it more difficult for patients to communicate with people. This study was aimed at investigating the effect of cochlear implants (CIs) on tinnitus distress and psychological comorbidities in patients with profound BD. This multicenter retrospective study reviewed 51 patients with severe postlingual BD who underwent cochlear implantation; 49 patients underwent unilateral cochlear implantation, and 2 patients underwent bilateral cochlear implantation. The patients were asked to complete all the questionnaires, including the tinnitus handicap inventory (THI), the visual analog scale (VAS) score, the Hospital Anxiety and Depression Scale Questionnaire (HADS), the Categories of Auditory Performance (CAP), and the Speech Intelligibility Rating (SIR), at least 4 months after implantation when the CI was on or off, in approximately May-June 2019. In our study, 94% (48/51) of BD patients suffered from tinnitus before CI, and 77% (37/48) of them suffered from bilateral tinnitus. In addition, 50.9% (26/51) of the CI patients were suffering from anxiety, 52.9% (27/51) of them were suffering from depression (score≥8), and 66.7% (34/51) (27/51) of them were suffering from anxiety or depression. Cochlear implantation could reduce tinnitus more obviously when the CI was on than when the CI was off. Cochlear implantation also reduced anxiety/depression severity. There were significantly positive correlations between tinnitus severity and anxiety/depression severity before and after surgery. Moreover, hearing improvement is positively correlated with reduction level of tinnitus, the better hearing, and the lesser severity of tinnitus. Thus, along with effective restoration of deafferentation, cochlear implantation shows positive therapeutic effects on tinnitus and psychological comorbidities, providing a reference for future clinical and research work.http://dx.doi.org/10.1155/2021/6678863 |
| spellingShingle | Juanmei Yang Jing Song Xiang Zhao Carol Pang Ning Cong Zhao Han Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients Neural Plasticity |
| title | Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients |
| title_full | Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients |
| title_fullStr | Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients |
| title_full_unstemmed | Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients |
| title_short | Restoration of Deafferentation Reduces Tinnitus, Anxiety, and Depression: A Retrospective Study on Cochlear Implant Patients |
| title_sort | restoration of deafferentation reduces tinnitus anxiety and depression a retrospective study on cochlear implant patients |
| url | http://dx.doi.org/10.1155/2021/6678863 |
| work_keys_str_mv | AT juanmeiyang restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients AT jingsong restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients AT xiangzhao restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients AT carolpang restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients AT ningcong restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients AT zhaohan restorationofdeafferentationreducestinnitusanxietyanddepressionaretrospectivestudyoncochlearimplantpatients |