Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s.
In promoting genomic medicine, genomic literacy, which is the public's ability to acquire and utilize the knowledge and skills related to genetics and genomes, requires urgent improvement. This study determined how the three components of genomic literacy (genetic/genomic knowledge, health nume...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0283432 |
| _version_ | 1797843071255183360 |
|---|---|
| author | Tomomi Miyoshi Masaki Watanabe |
| author_facet | Tomomi Miyoshi Masaki Watanabe |
| author_sort | Tomomi Miyoshi |
| collection | DOAJ |
| description | In promoting genomic medicine, genomic literacy, which is the public's ability to acquire and utilize the knowledge and skills related to genetics and genomes, requires urgent improvement. This study determined how the three components of genomic literacy (genetic/genomic knowledge, health numeracy, and interactive and critical health literacy) are associated with risk and benefit perception for genetic testing and decision-making related to genetic testing. Using an online questionnaire, we surveyed genetic/genomic knowledge, health numeracy, interactive and critical health literacy, risk and benefit perception of genetic testing, and intention toward genetic testing of 857 Japanese citizens (aged 20-39). A vignette was created to measure the intention toward genetic testing, and respondents were asked about their willingness to undergo genetic testing and to share the results with their partners and children. The path analysis, which was done by creating a path diagram revealing the relationship of the three components with risk and benefit perception, revealed that genetic and genomic knowledge and interactive and critical health literacy affected the respondents' intention to undergo genetic testing via recognition of the benefits of such testing. Further, it was suggested that health numeracy affects benefit perception through risk perception toward genetic testing. However, the goodness of fit of this model for the intention of conveying positive results to partners and children was relatively low, thus indicating that the hypothetical model needs to be reexamined. |
| first_indexed | 2024-04-09T16:58:33Z |
| format | Article |
| id | doaj.art-cb155a803a294e46a113cdc0cbcedb89 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-09T16:58:33Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-cb155a803a294e46a113cdc0cbcedb892023-04-21T05:34:18ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01183e028343210.1371/journal.pone.0283432Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s.Tomomi MiyoshiMasaki WatanabeIn promoting genomic medicine, genomic literacy, which is the public's ability to acquire and utilize the knowledge and skills related to genetics and genomes, requires urgent improvement. This study determined how the three components of genomic literacy (genetic/genomic knowledge, health numeracy, and interactive and critical health literacy) are associated with risk and benefit perception for genetic testing and decision-making related to genetic testing. Using an online questionnaire, we surveyed genetic/genomic knowledge, health numeracy, interactive and critical health literacy, risk and benefit perception of genetic testing, and intention toward genetic testing of 857 Japanese citizens (aged 20-39). A vignette was created to measure the intention toward genetic testing, and respondents were asked about their willingness to undergo genetic testing and to share the results with their partners and children. The path analysis, which was done by creating a path diagram revealing the relationship of the three components with risk and benefit perception, revealed that genetic and genomic knowledge and interactive and critical health literacy affected the respondents' intention to undergo genetic testing via recognition of the benefits of such testing. Further, it was suggested that health numeracy affects benefit perception through risk perception toward genetic testing. However, the goodness of fit of this model for the intention of conveying positive results to partners and children was relatively low, thus indicating that the hypothetical model needs to be reexamined.https://doi.org/10.1371/journal.pone.0283432 |
| spellingShingle | Tomomi Miyoshi Masaki Watanabe Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. PLoS ONE |
| title | Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. |
| title_full | Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. |
| title_fullStr | Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. |
| title_full_unstemmed | Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. |
| title_short | Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s. |
| title_sort | impact of genomic literacy components on genetic testing decision making in the general japanese population in the 20s and 30s |
| url | https://doi.org/10.1371/journal.pone.0283432 |
| work_keys_str_mv | AT tomomimiyoshi impactofgenomicliteracycomponentsongenetictestingdecisionmakinginthegeneraljapanesepopulationinthe20sand30s AT masakiwatanabe impactofgenomicliteracycomponentsongenetictestingdecisionmakinginthegeneraljapanesepopulationinthe20sand30s |