Research progress of astragaloside IV in the treatment of atopic diseases
Atopic disease is a kind of abnormal immune reaction caused by tissue damage and physiological dysfunction caused by allergens. Atopic diseases involve many systems and have obvious genetic tendencies, threatening the quality of life, health, and life safety of human beings. Astragalus membranaceus...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
|
| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222013786 |
| _version_ | 1811180260935335936 |
|---|---|
| author | Shencun Yu Wendong Peng Fanghong Qiu Guiju Zhang |
| author_facet | Shencun Yu Wendong Peng Fanghong Qiu Guiju Zhang |
| author_sort | Shencun Yu |
| collection | DOAJ |
| description | Atopic disease is a kind of abnormal immune reaction caused by tissue damage and physiological dysfunction caused by allergens. Atopic diseases involve many systems and have obvious genetic tendencies, threatening the quality of life, health, and life safety of human beings. Astragalus membranaceus is an ancient and commonly used traditional Chinese medicine widely used in allergic diseases. Astragaloside IV is one of the main active ingredients in Astragalus membranaceus and is an important index component for evaluating the quality of Astragalus membranaceus and Astragalus membranaceus preparations at present. It has good antiallergic and immunomodulatory effects. Therefore, this paper reviews and summarizes the mechanism of action, pharmacokinetics, and drug optimization research progress of astragaloside IV in the treatment of atopic diseases. |
| first_indexed | 2024-04-11T06:47:25Z |
| format | Article |
| id | doaj.art-cb15da5b87224c80aa8b601e003adc2b |
| institution | Directory Open Access Journal |
| issn | 0753-3322 |
| language | English |
| last_indexed | 2024-04-11T06:47:25Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedicine & Pharmacotherapy |
| spelling | doaj.art-cb15da5b87224c80aa8b601e003adc2b2022-12-22T04:39:19ZengElsevierBiomedicine & Pharmacotherapy0753-33222022-12-01156113989Research progress of astragaloside IV in the treatment of atopic diseasesShencun Yu0Wendong Peng1Fanghong Qiu2Guiju Zhang3Shandong University of Traditional Chinese Medicine, ChinaShandong University of Traditional Chinese Medicine, ChinaShandong University of Traditional Chinese Medicine, ChinaCorresponding author.; Shandong University of Traditional Chinese Medicine, ChinaAtopic disease is a kind of abnormal immune reaction caused by tissue damage and physiological dysfunction caused by allergens. Atopic diseases involve many systems and have obvious genetic tendencies, threatening the quality of life, health, and life safety of human beings. Astragalus membranaceus is an ancient and commonly used traditional Chinese medicine widely used in allergic diseases. Astragaloside IV is one of the main active ingredients in Astragalus membranaceus and is an important index component for evaluating the quality of Astragalus membranaceus and Astragalus membranaceus preparations at present. It has good antiallergic and immunomodulatory effects. Therefore, this paper reviews and summarizes the mechanism of action, pharmacokinetics, and drug optimization research progress of astragaloside IV in the treatment of atopic diseases.http://www.sciencedirect.com/science/article/pii/S0753332222013786Astragaloside IVAtopic diseaseAtopic marchPharmacological mechanism |
| spellingShingle | Shencun Yu Wendong Peng Fanghong Qiu Guiju Zhang Research progress of astragaloside IV in the treatment of atopic diseases Biomedicine & Pharmacotherapy Astragaloside IV Atopic disease Atopic march Pharmacological mechanism |
| title | Research progress of astragaloside IV in the treatment of atopic diseases |
| title_full | Research progress of astragaloside IV in the treatment of atopic diseases |
| title_fullStr | Research progress of astragaloside IV in the treatment of atopic diseases |
| title_full_unstemmed | Research progress of astragaloside IV in the treatment of atopic diseases |
| title_short | Research progress of astragaloside IV in the treatment of atopic diseases |
| title_sort | research progress of astragaloside iv in the treatment of atopic diseases |
| topic | Astragaloside IV Atopic disease Atopic march Pharmacological mechanism |
| url | http://www.sciencedirect.com/science/article/pii/S0753332222013786 |
| work_keys_str_mv | AT shencunyu researchprogressofastragalosideivinthetreatmentofatopicdiseases AT wendongpeng researchprogressofastragalosideivinthetreatmentofatopicdiseases AT fanghongqiu researchprogressofastragalosideivinthetreatmentofatopicdiseases AT guijuzhang researchprogressofastragalosideivinthetreatmentofatopicdiseases |