Cortex integrity relevance in muscle synergies in severe chronic stroke
Background: Recent experimental evidence has indicated that the motor system coordinates muscle activations through a linear combination of muscle synergies that are specified at the spinal or brainstem networks level. After stroke upper limb impairment is characterized by abnormal patterns of muscl...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-09-01
|
| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00744/full |
| _version_ | 1818548188007628800 |
|---|---|
| author | Eliana eGarcía-Cossio Doris eBroetz Niels eBirbaumer Niels eBirbaumer Niels eBirbaumer Ander eRamos-Murguialday Ander eRamos-Murguialday |
| author_facet | Eliana eGarcía-Cossio Doris eBroetz Niels eBirbaumer Niels eBirbaumer Niels eBirbaumer Ander eRamos-Murguialday Ander eRamos-Murguialday |
| author_sort | Eliana eGarcía-Cossio |
| collection | DOAJ |
| description | Background: Recent experimental evidence has indicated that the motor system coordinates muscle activations through a linear combination of muscle synergies that are specified at the spinal or brainstem networks level. After stroke upper limb impairment is characterized by abnormal patterns of muscle activations or synergies. Objective: This study aimed at characterizing the muscle synergies in severely affected chronic stroke patients. Furthermore, the influence of integrity of the sensorimotor cortex on synergy modularity and its relation with motor impairment was evaluated. Methods: Surface electromyography from 33 severely impaired chronic stroke patients was recorded during six bilateral movements. Muscle synergies were extracted and synergy patterns were correlated with motor impairment scales. Results: Muscle synergies extracted revealed different physiological patterns dependent on the preservation of the sensorimotor cortex. Patients without intact sensorimotor cortex showed a high preservation of muscle synergies. On the contrary, patients with intact sensorimotor cortex showed poorer muscle synergies preservation and an increase in new generated synergies. Furthermore, the preservation of muscle synergies correlated positively with hand functionality in patients with intact sensorimotor cortex and subcortical lesions only.Conclusions: Our results indicate that severely paralyzed chronic stroke patient with intact sensorimotor cortex might sculpt new synergy patterns as a response to maladaptive compensatory strategies. |
| first_indexed | 2024-12-12T08:16:35Z |
| format | Article |
| id | doaj.art-cb20569a0e154df9a5fa1e1a6b7da3ed |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-12T08:16:35Z |
| publishDate | 2014-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-cb20569a0e154df9a5fa1e1a6b7da3ed2022-12-22T00:31:33ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612014-09-01810.3389/fnhum.2014.00744109299Cortex integrity relevance in muscle synergies in severe chronic strokeEliana eGarcía-Cossio0Doris eBroetz1Niels eBirbaumer2Niels eBirbaumer3Niels eBirbaumer4Ander eRamos-Murguialday5Ander eRamos-Murguialday6University of TübingenUniversity of TübingenUniversity of TübingenUniversity of TübingenOspedale San Camillo, Istituto di Ricovero e Cura a Carattere ScientificoUniversity of TübingenTECNALIABackground: Recent experimental evidence has indicated that the motor system coordinates muscle activations through a linear combination of muscle synergies that are specified at the spinal or brainstem networks level. After stroke upper limb impairment is characterized by abnormal patterns of muscle activations or synergies. Objective: This study aimed at characterizing the muscle synergies in severely affected chronic stroke patients. Furthermore, the influence of integrity of the sensorimotor cortex on synergy modularity and its relation with motor impairment was evaluated. Methods: Surface electromyography from 33 severely impaired chronic stroke patients was recorded during six bilateral movements. Muscle synergies were extracted and synergy patterns were correlated with motor impairment scales. Results: Muscle synergies extracted revealed different physiological patterns dependent on the preservation of the sensorimotor cortex. Patients without intact sensorimotor cortex showed a high preservation of muscle synergies. On the contrary, patients with intact sensorimotor cortex showed poorer muscle synergies preservation and an increase in new generated synergies. Furthermore, the preservation of muscle synergies correlated positively with hand functionality in patients with intact sensorimotor cortex and subcortical lesions only.Conclusions: Our results indicate that severely paralyzed chronic stroke patient with intact sensorimotor cortex might sculpt new synergy patterns as a response to maladaptive compensatory strategies.http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00744/fullStrokeNeurorehabilitationmuscle synergieslesion locationFMA |
| spellingShingle | Eliana eGarcía-Cossio Doris eBroetz Niels eBirbaumer Niels eBirbaumer Niels eBirbaumer Ander eRamos-Murguialday Ander eRamos-Murguialday Cortex integrity relevance in muscle synergies in severe chronic stroke Frontiers in Human Neuroscience Stroke Neurorehabilitation muscle synergies lesion location FMA |
| title | Cortex integrity relevance in muscle synergies in severe chronic stroke |
| title_full | Cortex integrity relevance in muscle synergies in severe chronic stroke |
| title_fullStr | Cortex integrity relevance in muscle synergies in severe chronic stroke |
| title_full_unstemmed | Cortex integrity relevance in muscle synergies in severe chronic stroke |
| title_short | Cortex integrity relevance in muscle synergies in severe chronic stroke |
| title_sort | cortex integrity relevance in muscle synergies in severe chronic stroke |
| topic | Stroke Neurorehabilitation muscle synergies lesion location FMA |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00744/full |
| work_keys_str_mv | AT elianaegarciacossio cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT dorisebroetz cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT nielsebirbaumer cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT nielsebirbaumer cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT nielsebirbaumer cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT andereramosmurguialday cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke AT andereramosmurguialday cortexintegrityrelevanceinmusclesynergiesinseverechronicstroke |