Backbone-independent NMR resonance assignments of methyl probes in large proteins
Here, the authors present Methyl Assignments Using Satisfiability (MAUS), a method for the assignment of methyl groups using raw NOE data. They use eight proteins in the 10–45 kDa size range as test cases and show that MAUS yields 100% accurate assignments at high completeness levels.
Main Authors: | Santrupti Nerli, Viviane S. De Paula, Andrew C. McShan, Nikolaos G. Sgourakis |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-20984-0 |
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