The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation

The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation

Introduction: The mitochondrial uniporter (MCU) Ca2+ ion channel represents the primary means for Ca2+ uptake by mitochondria. Mitochondrial matrix Ca2+ plays critical roles in mitochondrial bioenergetics by impinging upon respiration, energy production and flux of biochemical intermediates through...

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Bibliographic Details
Main Authors:	Emily Fernandez Garcia, Usha Paudel, Michael C. Noji, Caitlyn E. Bowman, Anil K. Rustgi, Jason R. Pitarresi, Kathryn E. Wellen, Zolt Arany, Jillian S. Weissenrieder, J. Kevin Foskett
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	mitochondria uniporter calcium cancer metabolism stable isotope tracing
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1082213/full

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