A New Multi-Component Solid of Atorvastatin Calcium with a Dipicolinic Acid Coformer for Improving the Water Solubility

Atorvastatin calcium is a potent active pharmaceutical ingredient that reduces blood cholesterol levels. However, oral bioavailability is low because it is difficult to dissolve in water. Therefore, further research to increase the solubility of the drug is needed to improve its bioavailability...

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Bibliographic Details
Main Authors: Yudi Wicaksono, Ari Satia Nugraha, Eka Deddy Irawan, Nadifa Nada, Sofyan Dimas Nurhansyah
Format: Article
Language:English
Published: Universitas Indonesia 2023-05-01
Series:International Journal of Technology
Subjects:
Online Access:https://ijtech.eng.ui.ac.id/article/view/5088