Von Willebrand Factor and ADAMTS-13 Are Associated with the Severity of COVID-19 Disease

Von Willebrand Factor and ADAMTS-13 Are Associated with the Severity of COVID-19 Disease

Coagulopathy in COVID-19 patients is presumably based on systemic hypercoagulation with the inflammatory response. As a result of endothelial dysfunction, tissue factor and von Willebrand factor (vWF) are released into the blood stream, which leads to prothrombinase activation. The vWF/ADAMTS-13 rat...

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Bibliographic Details
Main Authors: Nataliya Dolgushina, Elena Gorodnova, Olga Beznoshenco, Andrey Romanov, Irina Menzhinskaya, Lyubov Krechetova, Gennady Sukhikh
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Clinical Medicine
Subjects:
COVID-19
von Willebrand factor
ADAMTS-13
hypercoagulation
thrombosis
Online Access:https://www.mdpi.com/2077-0383/11/14/4006

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