RP11-296E3.2 acts as an important molecular chaperone for YBX1 and promotes colorectal cancer proliferation and metastasis by activating STAT3

RP11-296E3.2 acts as an important molecular chaperone for YBX1 and promotes colorectal cancer proliferation and metastasis by activating STAT3

Abstract Background RP11-296E3.2 is a novel long noncoding RNA (lncRNA) associated with colorectal cancer (CRC) metastasis, that was reported in our previous clinical studies. However, the mechanisms of RP11-296E3.2 in colorectal tumorigenesis remain elusive. Methods RNA sequencing (RNA-seq), Fluore...

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Bibliographic Details
Main Authors: Qian Shi, Ying He, Shouyu He, Jingjing Li, Ji Xia, Tianwei Chen, Lixia Huo, Yuhang Ling, Qinchen Liu, Wei Zang, Qiang Wang, Chengwu Tang, Xiang Wang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Translational Medicine
Subjects:
CRC
Metastasis
Proliferation
RP11-296E3.2/YBX1
STAT3 transcription
Online Access:https://doi.org/10.1186/s12967-023-04267-4

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