Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves
Psidium myrsinites DC. is species known as "araçá", from the Cerrado (savanna) biome in Brazil. It is commonly used as a medicinal plant in the treatment of diarrhea because of its astringent properties. The aims of this study were to carry out phytochemical screening with an exploratory p...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Uberlândia
2017-09-01
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| Series: | Bioscience Journal |
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| Online Access: | http://www.seer.ufu.br/index.php/biosciencejournal/article/view/34763 |
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| author | Emanuelle Rosário Brito Durães Cássia de Oliveira Clementino Leonardo Rodrigues Fari Luciana Machado Ramos Marilene Silva Oliveira Joelma Abadia Marciano de Paula Plínio Lázaro Faleiro Naves |
| author_facet | Emanuelle Rosário Brito Durães Cássia de Oliveira Clementino Leonardo Rodrigues Fari Luciana Machado Ramos Marilene Silva Oliveira Joelma Abadia Marciano de Paula Plínio Lázaro Faleiro Naves |
| author_sort | Emanuelle Rosário Brito Durães |
| collection | DOAJ |
| description | Psidium myrsinites DC. is species known as "araçá", from the Cerrado (savanna) biome in Brazil. It is commonly used as a medicinal plant in the treatment of diarrhea because of its astringent properties. The aims of this study were to carry out phytochemical screening with an exploratory purpose; to investigate toxicity by brine shrimp (Artemia salina) lethality bioassay; and to evaluate antimicrobial activity against Gram-positive and Gram-negative bacteria by determining the minimum inhibitory concentration of the essential oil, acetonic and ethanolic crude extracts, and the fractions obtained with organic solvents of Psidium myrsinites DC. leaves. The phytochemical profile determined the major classes of secondary metabolites present as phenolic compounds (tannins, coumarins, flavonoids, anthraquinone glycosides and terpene compounds). The essential oil and hexane fraction demonstrated a level of strong and mild toxicity respectively, thus encouraging further research with isolated substances from them. The crude ethanolic and acetonic extracts, and hexane fractions, chloroform intermediary, ethyl acetate and aqueous fraction from crude acetonic extract showed the best inhibitory effect on bacterial growth of Gram-positive bacteria with minimum inhibitory concentrations ranging between 62.5 and 250 μg.mL-1. However, the presence of secondary compounds such as tannins, flavonoids and terpenes is probably associated with the inhibitory effect on tested microorganisms, which could justify the medicinal use of the leaves of this species. |
| first_indexed | 2024-12-24T03:15:24Z |
| format | Article |
| id | doaj.art-cb3571c023fc4d25b9769746d3c93c76 |
| institution | Directory Open Access Journal |
| issn | 1981-3163 |
| language | English |
| last_indexed | 2024-12-24T03:15:24Z |
| publishDate | 2017-09-01 |
| publisher | Universidade Federal de Uberlândia |
| record_format | Article |
| series | Bioscience Journal |
| spelling | doaj.art-cb3571c023fc4d25b9769746d3c93c762022-12-21T17:17:40ZengUniversidade Federal de UberlândiaBioscience Journal1981-31632017-09-0133510.14393/BJ-v33n5a2017-3476334763Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leavesEmanuelle Rosário Brito DurãesCássia de Oliveira ClementinoLeonardo Rodrigues FariLuciana Machado RamosMarilene Silva OliveiraJoelma Abadia Marciano de PaulaPlínio Lázaro Faleiro NavesPsidium myrsinites DC. is species known as "araçá", from the Cerrado (savanna) biome in Brazil. It is commonly used as a medicinal plant in the treatment of diarrhea because of its astringent properties. The aims of this study were to carry out phytochemical screening with an exploratory purpose; to investigate toxicity by brine shrimp (Artemia salina) lethality bioassay; and to evaluate antimicrobial activity against Gram-positive and Gram-negative bacteria by determining the minimum inhibitory concentration of the essential oil, acetonic and ethanolic crude extracts, and the fractions obtained with organic solvents of Psidium myrsinites DC. leaves. The phytochemical profile determined the major classes of secondary metabolites present as phenolic compounds (tannins, coumarins, flavonoids, anthraquinone glycosides and terpene compounds). The essential oil and hexane fraction demonstrated a level of strong and mild toxicity respectively, thus encouraging further research with isolated substances from them. The crude ethanolic and acetonic extracts, and hexane fractions, chloroform intermediary, ethyl acetate and aqueous fraction from crude acetonic extract showed the best inhibitory effect on bacterial growth of Gram-positive bacteria with minimum inhibitory concentrations ranging between 62.5 and 250 μg.mL-1. However, the presence of secondary compounds such as tannins, flavonoids and terpenes is probably associated with the inhibitory effect on tested microorganisms, which could justify the medicinal use of the leaves of this species.http://www.seer.ufu.br/index.php/biosciencejournal/article/view/34763psidium myrsinites d.cessential oiltanninsartemia salinaminimum inhibitory concentration |
| spellingShingle | Emanuelle Rosário Brito Durães Cássia de Oliveira Clementino Leonardo Rodrigues Fari Luciana Machado Ramos Marilene Silva Oliveira Joelma Abadia Marciano de Paula Plínio Lázaro Faleiro Naves Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves Bioscience Journal psidium myrsinites d.c essential oil tannins artemia salina minimum inhibitory concentration |
| title | Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves |
| title_full | Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves |
| title_fullStr | Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves |
| title_full_unstemmed | Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves |
| title_short | Phytochemical study, toxicity and antimicrobial activity of Psidium myrsinites DC. (Myrtaceae) leaves |
| title_sort | phytochemical study toxicity and antimicrobial activity of psidium myrsinites dc myrtaceae leaves |
| topic | psidium myrsinites d.c essential oil tannins artemia salina minimum inhibitory concentration |
| url | http://www.seer.ufu.br/index.php/biosciencejournal/article/view/34763 |
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