Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy

When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthoc...

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Main Authors: Małgorzata Piątek, Renata Polaniak, Agata Kiciak, Wiktoria Staśkiewicz, Mateusz Grajek
Format: Article
Language:English
Published: Kazimierz Wielki University 2022-07-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/39167
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author Małgorzata Piątek
Renata Polaniak
Agata Kiciak
Wiktoria Staśkiewicz
Mateusz Grajek
author_facet Małgorzata Piątek
Renata Polaniak
Agata Kiciak
Wiktoria Staśkiewicz
Mateusz Grajek
author_sort Małgorzata Piątek
collection DOAJ
description When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthocyanins are a large group of ingredients contained in plants that do not have a nutritional function, but play a significant role in the regulation of metabolic processes in the human body, which has a multidirectional pro-health and preventive effect in relation to many diseases, especially cancer. High hopes in chemoprevention are associated with the biological activity of the most common representative of anthocyanins, i.e. cyanidin-3-glucoside (Cy3G). Most of the studies on Cy3G bioactivity come mainly from in vitro cell line tests and in vivo experimental studies on rodents. Studies of the biological activity of Cy3G most often include: the process of free radical absorption, anti-inflammatory, anticoagulant, insulinotropic, antimicrobial, chemotherapeutic and epigenetic effects. This publication summarizes the results of in vitro studies conducted on various cancer cell lines, which prove the antiproliferative, anti-inflammatory and chemopreventive activity of Cy3G.
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spelling doaj.art-cb390a8fd09d477283a402392890a0fc2022-12-22T00:59:14ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-07-0112710.12775/JEHS.2022.12.07.072Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapyMałgorzata Piątek0Renata Polaniak1Agata Kiciak2Wiktoria Staśkiewicz3Mateusz Grajek4Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra DietetykiŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Żywienia CzłowiekaŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Technologii i Oceny Jakości ŻywnościŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Technologii i Oceny Jakości ŻywnościŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Polityki Zdrowia Publicznego, Zakład Zdrowia Publicznego When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthocyanins are a large group of ingredients contained in plants that do not have a nutritional function, but play a significant role in the regulation of metabolic processes in the human body, which has a multidirectional pro-health and preventive effect in relation to many diseases, especially cancer. High hopes in chemoprevention are associated with the biological activity of the most common representative of anthocyanins, i.e. cyanidin-3-glucoside (Cy3G). Most of the studies on Cy3G bioactivity come mainly from in vitro cell line tests and in vivo experimental studies on rodents. Studies of the biological activity of Cy3G most often include: the process of free radical absorption, anti-inflammatory, anticoagulant, insulinotropic, antimicrobial, chemotherapeutic and epigenetic effects. This publication summarizes the results of in vitro studies conducted on various cancer cell lines, which prove the antiproliferative, anti-inflammatory and chemopreventive activity of Cy3G. https://apcz.umk.pl/JEHS/article/view/39167Anthocyaninsglucoside-3-cyanidinchemopreventionantioxidant
spellingShingle Małgorzata Piątek
Renata Polaniak
Agata Kiciak
Wiktoria Staśkiewicz
Mateusz Grajek
Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
Journal of Education, Health and Sport
Anthocyanins
glucoside-3-cyanidin
chemoprevention
antioxidant
title Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
title_full Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
title_fullStr Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
title_full_unstemmed Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
title_short Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
title_sort glucoside 3 cyanidin cy3g and its importance in cancer therapy
topic Anthocyanins
glucoside-3-cyanidin
chemoprevention
antioxidant
url https://apcz.umk.pl/JEHS/article/view/39167
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AT renatapolaniak glucoside3cyanidincy3ganditsimportanceincancertherapy
AT agatakiciak glucoside3cyanidincy3ganditsimportanceincancertherapy
AT wiktoriastaskiewicz glucoside3cyanidincy3ganditsimportanceincancertherapy
AT mateuszgrajek glucoside3cyanidincy3ganditsimportanceincancertherapy