Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy
When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthoc...
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Format: | Article |
Language: | English |
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Kazimierz Wielki University
2022-07-01
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Series: | Journal of Education, Health and Sport |
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Online Access: | https://apcz.umk.pl/JEHS/article/view/39167 |
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author | Małgorzata Piątek Renata Polaniak Agata Kiciak Wiktoria Staśkiewicz Mateusz Grajek |
author_facet | Małgorzata Piątek Renata Polaniak Agata Kiciak Wiktoria Staśkiewicz Mateusz Grajek |
author_sort | Małgorzata Piątek |
collection | DOAJ |
description |
When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthocyanins are a large group of ingredients contained in plants that do not have a nutritional function, but play a significant role in the regulation of metabolic processes in the human body, which has a multidirectional pro-health and preventive effect in relation to many diseases, especially cancer. High hopes in chemoprevention are associated with the biological activity of the most common representative of anthocyanins, i.e. cyanidin-3-glucoside (Cy3G). Most of the studies on Cy3G bioactivity come mainly from in vitro cell line tests and in vivo experimental studies on rodents. Studies of the biological activity of Cy3G most often include: the process of free radical absorption, anti-inflammatory, anticoagulant, insulinotropic, antimicrobial, chemotherapeutic and epigenetic effects. This publication summarizes the results of in vitro studies conducted on various cancer cell lines, which prove the antiproliferative, anti-inflammatory and chemopreventive activity of Cy3G.
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first_indexed | 2024-12-11T16:04:02Z |
format | Article |
id | doaj.art-cb390a8fd09d477283a402392890a0fc |
institution | Directory Open Access Journal |
issn | 2391-8306 |
language | English |
last_indexed | 2024-12-11T16:04:02Z |
publishDate | 2022-07-01 |
publisher | Kazimierz Wielki University |
record_format | Article |
series | Journal of Education, Health and Sport |
spelling | doaj.art-cb390a8fd09d477283a402392890a0fc2022-12-22T00:59:14ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-07-0112710.12775/JEHS.2022.12.07.072Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapyMałgorzata Piątek0Renata Polaniak1Agata Kiciak2Wiktoria Staśkiewicz3Mateusz Grajek4Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra DietetykiŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Żywienia CzłowiekaŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Technologii i Oceny Jakości ŻywnościŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Dietetyki, Zakład Technologii i Oceny Jakości ŻywnościŚląski Uniwersytet Medyczny w Katowicach, Wydział Nauk o Zdrowiu w Bytomiu, Katedra Polityki Zdrowia Publicznego, Zakład Zdrowia Publicznego When analyzing the structure of cancer incidence in Poland, it is extremely important to take chemopreventive actions as early as possible, which are aimed at reducing the incidence of the most common cancers, focusing on the prevention and use of natural bioactive factors contained in food. Anthocyanins are a large group of ingredients contained in plants that do not have a nutritional function, but play a significant role in the regulation of metabolic processes in the human body, which has a multidirectional pro-health and preventive effect in relation to many diseases, especially cancer. High hopes in chemoprevention are associated with the biological activity of the most common representative of anthocyanins, i.e. cyanidin-3-glucoside (Cy3G). Most of the studies on Cy3G bioactivity come mainly from in vitro cell line tests and in vivo experimental studies on rodents. Studies of the biological activity of Cy3G most often include: the process of free radical absorption, anti-inflammatory, anticoagulant, insulinotropic, antimicrobial, chemotherapeutic and epigenetic effects. This publication summarizes the results of in vitro studies conducted on various cancer cell lines, which prove the antiproliferative, anti-inflammatory and chemopreventive activity of Cy3G. https://apcz.umk.pl/JEHS/article/view/39167Anthocyaninsglucoside-3-cyanidinchemopreventionantioxidant |
spellingShingle | Małgorzata Piątek Renata Polaniak Agata Kiciak Wiktoria Staśkiewicz Mateusz Grajek Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy Journal of Education, Health and Sport Anthocyanins glucoside-3-cyanidin chemoprevention antioxidant |
title | Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy |
title_full | Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy |
title_fullStr | Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy |
title_full_unstemmed | Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy |
title_short | Glucoside-3-cyanidin (Cy3G) and its importance in cancer therapy |
title_sort | glucoside 3 cyanidin cy3g and its importance in cancer therapy |
topic | Anthocyanins glucoside-3-cyanidin chemoprevention antioxidant |
url | https://apcz.umk.pl/JEHS/article/view/39167 |
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