Predicted regulatory SNPs reveal potential drug targets and novel companion diagnostics in psoriasis

Predicted regulatory SNPs reveal potential drug targets and novel companion diagnostics in psoriasis

Psoriasis is an autoimmune disease associated with interleukins, their receptors, key transcription factors and more recently, antimicrobial peptides (AMPs). Cathelicidin LL-37 is an AMP proposed to play a fundamental role in psoriasis etiology. With our proprietary software SNPClinic v.1.0, we anal...

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Bibliographic Details
Main Authors: Andrea Virginia Ruiz Ramírez, M. Sc., Adolfo Flores-Saiffe Farías, M. Sc., Rocío del Carmen Chávez Álvarez, Ph. D., Ernesto Prado Montes de Oca, M.Sc., Ph.D.
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Psoriasis
Bioinformatics
Gene expression regulation
Single nucleotide polymorphism
Regulatory SNPs
Transcription factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909021000162

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