Disruption of Sarcoplasmic Reticulum‐Mitochondrial Contacts Underlies Contractile Dysfunction in Experimental and Human Atrial Fibrillation: A Key Role of Mitofusin 2

Disruption of Sarcoplasmic Reticulum‐Mitochondrial Contacts Underlies Contractile Dysfunction in Experimental and Human Atrial Fibrillation: A Key Role of Mitofusin 2

Background Atrial fibrillation (AF) is the most common and progressive tachyarrhythmia. Diabetes is a common risk factor for AF. Recent research findings revealed that microtubule network disruption underlies AF. The microtubule network mediates the contact between sarcoplasmic reticulum and mitocho...

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Bibliographic Details
Main Authors:	Jin Li, Xi Qi, Kennedy S. Ramos, Eva Lanters, Jaap Keijer, Natasja de Groot, Bianca Brundel, Deli Zhang
Format:	Article
Language:	English
Published:	Wiley 2022-10-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	atrial fibrillation diabetes Drosophila microtubules mitosusin 2 sarcoplasmic reticulum‐mitochondrial contacts
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.121.024478

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