Flagellar Hook Protein FlgE Induces Microvascular Hyperpermeability via Ectopic ATP Synthase β on Endothelial Surface

Flagellar Hook Protein FlgE Induces Microvascular Hyperpermeability via Ectopic ATP Synthase β on Endothelial Surface

We previously demonstrated the immunostimulatory efficacy of Pseudomonas aeruginosa flagellar hook protein FlgE on epithelial cells, presumably via ectopic ATP synthases or subunits ATP5B on cell membranes. Here, by using recombinant wild-type FlgE, mutant FlgE (FlgEM; bearing mutations on two postu...

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Bibliographic Details
Main Authors: Yuanyuan Li, Ying Shen, Yudan Zheng, Shundong Ji, Mengru Wang, Beibei Wang, Qingzhen Han, Yufeng Tian, Yiqiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
ATP synthase subunit β
ATP5B
flagellar hook protein
FlgE
vascular endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.724912/full

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