Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit
In this study the effect of prostaglandin F2 alpha analogue, dinoprost, on corpus luteal tissue in pseudopregnant rabbit was investigated. For this purpose, 42 mature female rabbits were randomly divided into 6 groups of 7 animals each. In 3 groups, on day 10 of pseudopregnancy, dinoprost (1mg/kg) w...
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Islamic Azad University, Tabriz Branch
2008-05-01
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Series: | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
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Online Access: | http://jvcp.iaut.ac.ir/article_518594_02b3309475350869b4edc99a10aa8cad.pdf |
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author | S.e Safavi M.H Khayat Nouri |
author_facet | S.e Safavi M.H Khayat Nouri |
author_sort | S.e Safavi |
collection | DOAJ |
description | In this study the effect of prostaglandin F2 alpha analogue, dinoprost, on corpus luteal tissue in pseudopregnant rabbit was investigated. For this purpose, 42 mature female rabbits were randomly divided into 6 groups of 7 animals each. In 3 groups, on day 10 of pseudopregnancy, dinoprost (1mg/kg) was injected intramuscularly and 24, 48 and 72 hours following injection respectively, the animals were necropsied. In the other three groups, normal saline solution was injected as control groups. In all groups, after blood sampling the animals were necropsied and their ovaries removed and weighed. Following sampling and fixation in 10% formalin solution, the tissue samples were stained by Hematoxylene & Eosine method and the corpora lutea were studied morphologically and morphometrically. Histomorphometrical study indicated that the diameter of corpus luteum decreased significantly (p |
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format | Article |
id | doaj.art-cb4fc768eeac4393a74b992f0047351d |
institution | Directory Open Access Journal |
issn | 2322-4746 2476-6984 |
language | fas |
last_indexed | 2024-12-14T00:33:11Z |
publishDate | 2008-05-01 |
publisher | Islamic Azad University, Tabriz Branch |
record_format | Article |
series | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
spelling | doaj.art-cb4fc768eeac4393a74b992f0047351d2022-12-21T23:24:46ZfasIslamic Azad University, Tabriz BranchĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī2322-47462476-69842008-05-0121 (5) بهار5968518594Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbitS.e Safavi0M.H Khayat Nouri1Department of Basic Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch, Tabriz, IranDepartment of Basic Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch, Tabriz, IranIn this study the effect of prostaglandin F2 alpha analogue, dinoprost, on corpus luteal tissue in pseudopregnant rabbit was investigated. For this purpose, 42 mature female rabbits were randomly divided into 6 groups of 7 animals each. In 3 groups, on day 10 of pseudopregnancy, dinoprost (1mg/kg) was injected intramuscularly and 24, 48 and 72 hours following injection respectively, the animals were necropsied. In the other three groups, normal saline solution was injected as control groups. In all groups, after blood sampling the animals were necropsied and their ovaries removed and weighed. Following sampling and fixation in 10% formalin solution, the tissue samples were stained by Hematoxylene & Eosine method and the corpora lutea were studied morphologically and morphometrically. Histomorphometrical study indicated that the diameter of corpus luteum decreased significantly (phttp://jvcp.iaut.ac.ir/article_518594_02b3309475350869b4edc99a10aa8cad.pdfPGF2 alphacorpus luteumpseudopregnancyRabbit |
spellingShingle | S.e Safavi M.H Khayat Nouri Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī PGF2 alpha corpus luteum pseudopregnancy Rabbit |
title | Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit |
title_full | Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit |
title_fullStr | Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit |
title_full_unstemmed | Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit |
title_short | Study of the effect of prostaglandin F2α analogue, Dinoprost, on cropus luteal tissue in pseudopregnant rabbit |
title_sort | study of the effect of prostaglandin f2α analogue dinoprost on cropus luteal tissue in pseudopregnant rabbit |
topic | PGF2 alpha corpus luteum pseudopregnancy Rabbit |
url | http://jvcp.iaut.ac.ir/article_518594_02b3309475350869b4edc99a10aa8cad.pdf |
work_keys_str_mv | AT sesafavi studyoftheeffectofprostaglandinf2aanaloguedinoprostoncropuslutealtissueinpseudopregnantrabbit AT mhkhayatnouri studyoftheeffectofprostaglandinf2aanaloguedinoprostoncropuslutealtissueinpseudopregnantrabbit |