Clinicopathological Significance of Cancer Stem Cell Markers (OCT-3/4 and SOX-2) in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma

Clinicopathological Significance of Cancer Stem Cell Markers (OCT-3/4 and SOX-2) in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma

Oral submucous fibrosis (OSMF) is highly prevalent in South East Asia with higher rates of malignant transformation in Indian subcontinent. Numerous biomarkers are now being studied to predict disease prognosis and detect malignant alterations at an early stage. Patients with clinically and biopsy-p...

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Bibliographic Details
Main Authors: Divyambika Catakapatri Venugopal, Cynthia Leslie Caleb, Nandhini Priyadarshini Kirupakaran, Vidyarani Shyamsundar, Soundharya Ravindran, Madhavan Yasasve, Arvind Krishnamurthy, Thamizhchelvan Harikrishnan, Sathasivasubramanian Sankarapandian, Vijayalakshmi Ramshankar
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
oral submucous fibrosis
immunohistochemistry
malignant transformation
real-time PCR
octamer-binding transcription factor 3/4 (OCT-3/4)
sex-determining region Y-box 2 (SOX-2)
Online Access:https://www.mdpi.com/2227-9059/11/4/1040

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