Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts

Background: Opium addiction, as a major health problem, has been reported in Middle East countries. Recently, contaminated opium has been reported as a probable source of lead poisoning. Thus, the aim of this study is to evaluate blood lead levels (BLL), liver enzymes, and hemoglobin (Hb) concentrat...

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Main Authors: Farzaneh Montazerifar, Mansour Karajibani, Maryam Lashkaripour, Manijeh Sayyad Mollashahi, Abbas Ali Niazi, Moghgan Soltan Mohammadi, Samaneh Rahimi Helari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:International Journal of Preventive Medicine
Subjects:
Online Access:http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2021;volume=12;issue=1;spage=3;epage=3;aulast=Montazerifar
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author Farzaneh Montazerifar
Mansour Karajibani
Maryam Lashkaripour
Manijeh Sayyad Mollashahi
Abbas Ali Niazi
Moghgan Soltan Mohammadi
Samaneh Rahimi Helari
author_facet Farzaneh Montazerifar
Mansour Karajibani
Maryam Lashkaripour
Manijeh Sayyad Mollashahi
Abbas Ali Niazi
Moghgan Soltan Mohammadi
Samaneh Rahimi Helari
author_sort Farzaneh Montazerifar
collection DOAJ
description Background: Opium addiction, as a major health problem, has been reported in Middle East countries. Recently, contaminated opium has been reported as a probable source of lead poisoning. Thus, the aim of this study is to evaluate blood lead levels (BLL), liver enzymes, and hemoglobin (Hb) concentrations in opium-dependent addicts with healthy controls. Methods: In a cross-sectional study, 75 opium-addicted men (case group) referred to Zahedan Baharan Hospital were evaluated. A group of 75 nonaddicted men were selected as a control group. BLL, Hb, and liver enzymes levels were measured. Body mass index (BMI) was also calculated. Results: The case group had elevated BLL compared to the controls (19.1 ± 1.6 vs. 9.1 ± 0.4; P < 0.0001). Hb concentrations were significantly lower in the patients compared to the controls (13.3 ± 1.6 vs. 15.1 ± 1.3; P < 0.0001). A positive correlation was found between BLL and opium addict duration in the case group (r = 0.52, P < 0.0001). Conclusions: Due to the contamination of opium to lead, it seems that opiate addicts are at risk of lead poisoning. Thus, it is recommended that the blood lead level is frequently monitored to control the adverse effects of poisoning and prevent lead accumulation.
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spelling doaj.art-cb54f37033b3496a9b0413726945ca6b2022-12-21T18:13:03ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132021-01-011213310.4103/ijpvm.IJPVM_303_18Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent AddictsFarzaneh MontazerifarMansour KarajibaniMaryam LashkaripourManijeh Sayyad MollashahiAbbas Ali NiaziMoghgan Soltan MohammadiSamaneh Rahimi HelariBackground: Opium addiction, as a major health problem, has been reported in Middle East countries. Recently, contaminated opium has been reported as a probable source of lead poisoning. Thus, the aim of this study is to evaluate blood lead levels (BLL), liver enzymes, and hemoglobin (Hb) concentrations in opium-dependent addicts with healthy controls. Methods: In a cross-sectional study, 75 opium-addicted men (case group) referred to Zahedan Baharan Hospital were evaluated. A group of 75 nonaddicted men were selected as a control group. BLL, Hb, and liver enzymes levels were measured. Body mass index (BMI) was also calculated. Results: The case group had elevated BLL compared to the controls (19.1 ± 1.6 vs. 9.1 ± 0.4; P < 0.0001). Hb concentrations were significantly lower in the patients compared to the controls (13.3 ± 1.6 vs. 15.1 ± 1.3; P < 0.0001). A positive correlation was found between BLL and opium addict duration in the case group (r = 0.52, P < 0.0001). Conclusions: Due to the contamination of opium to lead, it seems that opiate addicts are at risk of lead poisoning. Thus, it is recommended that the blood lead level is frequently monitored to control the adverse effects of poisoning and prevent lead accumulation.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2021;volume=12;issue=1;spage=3;epage=3;aulast=Montazerifarhemoglobinleadliver enzymesopium addiction
spellingShingle Farzaneh Montazerifar
Mansour Karajibani
Maryam Lashkaripour
Manijeh Sayyad Mollashahi
Abbas Ali Niazi
Moghgan Soltan Mohammadi
Samaneh Rahimi Helari
Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
International Journal of Preventive Medicine
hemoglobin
lead
liver enzymes
opium addiction
title Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
title_full Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
title_fullStr Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
title_full_unstemmed Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
title_short Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
title_sort blood lead levels hemoglobin and liver enzymes in opium dependent addicts
topic hemoglobin
lead
liver enzymes
opium addiction
url http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2021;volume=12;issue=1;spage=3;epage=3;aulast=Montazerifar
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AT manijehsayyadmollashahi bloodleadlevelshemoglobinandliverenzymesinopiumdependentaddicts
AT abbasaliniazi bloodleadlevelshemoglobinandliverenzymesinopiumdependentaddicts
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