Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft
Negative pressure wound therapy with intermittent instillation, especially with the addition of antibiotics in the case of infection, is a versatile treatment modality for the closure of wounds and can be used both primarily after débridement and secondarily after failure of muscle flap coverage. We...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-12-01
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| Series: | Journal of Vascular Surgery Cases and Innovative Techniques |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468428719300693 |
| _version_ | 1828877363802275840 |
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| author | Chrisovalantis Lakhiani, MD Christopher M. Fleury, MD Cara K. Black, BA David E. Janhofer, BS Cameron Akbari, MD Karen Kim Evans, MD |
| author_facet | Chrisovalantis Lakhiani, MD Christopher M. Fleury, MD Cara K. Black, BA David E. Janhofer, BS Cameron Akbari, MD Karen Kim Evans, MD |
| author_sort | Chrisovalantis Lakhiani, MD |
| collection | DOAJ |
| description | Negative pressure wound therapy with intermittent instillation, especially with the addition of antibiotics in the case of infection, is a versatile treatment modality for the closure of wounds and can be used both primarily after débridement and secondarily after failure of muscle flap coverage. We present a case in which negative pressure wound therapy with intermittent instillation of rifampin was used to successfully close a groin wound secondary to an infected prosthetic vascular graft that initially failed to close with a muscle flap. Consideration of this approach to wound closure and graft salvage is important because of the seriousness and relatively common incidence of prosthetic vascular graft infection after infrainguinal arterial bypass revascularization. Keywords: Negative pressure wound therapy, NPWT, VAC instill, Rifampin, Instillation |
| first_indexed | 2024-12-13T08:40:06Z |
| format | Article |
| id | doaj.art-cb5688629fa342329b1d23150e99cd87 |
| institution | Directory Open Access Journal |
| issn | 2468-4287 |
| language | English |
| last_indexed | 2024-12-13T08:40:06Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Vascular Surgery Cases and Innovative Techniques |
| spelling | doaj.art-cb5688629fa342329b1d23150e99cd872022-12-21T23:53:34ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872019-12-0154435437Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graftChrisovalantis Lakhiani, MD0Christopher M. Fleury, MD1Cara K. Black, BA2David E. Janhofer, BS3Cameron Akbari, MD4Karen Kim Evans, MD5Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Correspondence: Karen Kim Evans, MD, Associate Professor, Department of Plastic and Reconstructive Surgery, 3800 Reservoir Rd NW, Center for Wound Healing and Hyperbaric Medicine, 1st Fl, Bles Bldg, Washington, D.C. 20007; Center for Wound Healing and Hyperbaric Medicine, Department of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.Negative pressure wound therapy with intermittent instillation, especially with the addition of antibiotics in the case of infection, is a versatile treatment modality for the closure of wounds and can be used both primarily after débridement and secondarily after failure of muscle flap coverage. We present a case in which negative pressure wound therapy with intermittent instillation of rifampin was used to successfully close a groin wound secondary to an infected prosthetic vascular graft that initially failed to close with a muscle flap. Consideration of this approach to wound closure and graft salvage is important because of the seriousness and relatively common incidence of prosthetic vascular graft infection after infrainguinal arterial bypass revascularization. Keywords: Negative pressure wound therapy, NPWT, VAC instill, Rifampin, Instillationhttp://www.sciencedirect.com/science/article/pii/S2468428719300693 |
| spellingShingle | Chrisovalantis Lakhiani, MD Christopher M. Fleury, MD Cara K. Black, BA David E. Janhofer, BS Cameron Akbari, MD Karen Kim Evans, MD Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft Journal of Vascular Surgery Cases and Innovative Techniques |
| title | Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| title_full | Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| title_fullStr | Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| title_full_unstemmed | Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| title_short | Negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| title_sort | negative pressure wound therapy with intermittent instillation of rifampin for the treatment of an infected vascular bypass graft |
| url | http://www.sciencedirect.com/science/article/pii/S2468428719300693 |
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