Integrated multi-omics analyses reveal the altered transcriptomic characteristics of pulmonary macrophages in immunocompromised hosts with Pneumocystis pneumonia

Integrated multi-omics analyses reveal the altered transcriptomic characteristics of pulmonary macrophages in immunocompromised hosts with Pneumocystis pneumonia

IntroductionWith the extensive use of immunosuppressants, immunosuppression-associated pneumonitis including Pneumocystis jirovecii pneumonia (PCP) has received increasing attention. Though aberrant adaptive immunity has been considered as a key reason for opportunistic infections, the characteristi...

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Bibliographic Details
Main Authors:	Yawen Wang, Kang Li, Weichao Zhao, Yalan Liu, Ting Li, Hu-Qin Yang, Zhaohui Tong, Nan Song
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Immunology
Subjects:	Pneumocystis pneumonia glucocorticoids single-cell RNA sequencing macrophages immunosuppression
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179094/full

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