Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for metabolic disease

Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for metabolic disease

The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that can influence chemosensory cells lining the gastrointestinal tract. Specifically, hormone-releasing enteroendocrine cells...

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Bibliographic Details
Main Authors: Karly E. Masse, Van B. Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
enteroendocrine cells (EEC)
gut microbiota
short-chain fatty acids (SCFAs)
bile acids (BAs)
indoles
glucagon-like peptide-1
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1169624/full

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