Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea
Lyme disease is a tick-borne zoonotic disease caused by <i>Borrelia burgdorferi</i> sensu lato (s. l.) via transmission cycles involving competent tick vectors and vertebrate reservoirs. Here, we determined the prevalence and distribution of <i>Borrelia</i> genospecies in 738...
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MDPI AG
2020-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/9/11/866 |
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| author | Seong Yoon Kim Tae-Kyu Kim Tae Yun Kim Hee Il Lee |
| author_facet | Seong Yoon Kim Tae-Kyu Kim Tae Yun Kim Hee Il Lee |
| author_sort | Seong Yoon Kim |
| collection | DOAJ |
| description | Lyme disease is a tick-borne zoonotic disease caused by <i>Borrelia burgdorferi</i> sensu lato (s. l.) via transmission cycles involving competent tick vectors and vertebrate reservoirs. Here, we determined the prevalence and distribution of <i>Borrelia</i> genospecies in 738 ticks of at least three species from wild rodents in nine regions of the Republic of Korea (ROK). Ticks were analyzed using nested PCR targeting partial flagellin B gene sequences, followed by sequence analysis. The prevalence of <i>Borrelia</i> infection was 33.6%, and the most common genospecies were <i>B. afzelii</i> (62.5%), <i>B. valaisiana</i> (31.9%), <i>B. yangtzensis</i> (2.4%), <i>B. garinii</i> (1.6%), and <i>B. tanukii</i> (1.6%). <i>Borrelia afzelii</i> was found in all regions except Jeju Island; this predominant genospecies was found in the northern and central sampling regions. <i>Borrelia valaisiana</i>, <i>B. yangtzensis</i>, and <i>B. tanukii</i> were found only in the southern regions with <i>B. valaisiana</i> being the most common, whereas <i>B. yangtzensis</i> and <i>B. tanukii</i> were only found on Jeju Island. Our study is the first to describe the nationwide prevalence of <i>B. burgdorferi</i> s. l. in ticks from wild rodents in the ROK. Continuous surveillance in ticks, animals, humans, and different regions is required to avoid disease distribution and possible transmission to humans in the ROK. |
| first_indexed | 2024-03-10T15:24:59Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T15:24:59Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-cb5bafd221f1478494e083d2263393822023-11-20T18:10:14ZengMDPI AGPathogens2076-08172020-10-0191186610.3390/pathogens9110866Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of KoreaSeong Yoon Kim0Tae-Kyu Kim1Tae Yun Kim2Hee Il Lee3Division of Vectors and Parasitic Diseases, Bureau of Infectious Disease Diagnosis Control, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Cheongwon-gun, Cheongju-si 363-951, Chungcheongbuk-do 28159, KoreaDivision of Vectors and Parasitic Diseases, Bureau of Infectious Disease Diagnosis Control, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Cheongwon-gun, Cheongju-si 363-951, Chungcheongbuk-do 28159, KoreaDivision of Vectors and Parasitic Diseases, Bureau of Infectious Disease Diagnosis Control, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Cheongwon-gun, Cheongju-si 363-951, Chungcheongbuk-do 28159, KoreaDivision of Vectors and Parasitic Diseases, Bureau of Infectious Disease Diagnosis Control, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Cheongwon-gun, Cheongju-si 363-951, Chungcheongbuk-do 28159, KoreaLyme disease is a tick-borne zoonotic disease caused by <i>Borrelia burgdorferi</i> sensu lato (s. l.) via transmission cycles involving competent tick vectors and vertebrate reservoirs. Here, we determined the prevalence and distribution of <i>Borrelia</i> genospecies in 738 ticks of at least three species from wild rodents in nine regions of the Republic of Korea (ROK). Ticks were analyzed using nested PCR targeting partial flagellin B gene sequences, followed by sequence analysis. The prevalence of <i>Borrelia</i> infection was 33.6%, and the most common genospecies were <i>B. afzelii</i> (62.5%), <i>B. valaisiana</i> (31.9%), <i>B. yangtzensis</i> (2.4%), <i>B. garinii</i> (1.6%), and <i>B. tanukii</i> (1.6%). <i>Borrelia afzelii</i> was found in all regions except Jeju Island; this predominant genospecies was found in the northern and central sampling regions. <i>Borrelia valaisiana</i>, <i>B. yangtzensis</i>, and <i>B. tanukii</i> were found only in the southern regions with <i>B. valaisiana</i> being the most common, whereas <i>B. yangtzensis</i> and <i>B. tanukii</i> were only found on Jeju Island. Our study is the first to describe the nationwide prevalence of <i>B. burgdorferi</i> s. l. in ticks from wild rodents in the ROK. Continuous surveillance in ticks, animals, humans, and different regions is required to avoid disease distribution and possible transmission to humans in the ROK.https://www.mdpi.com/2076-0817/9/11/866lyme disease<i>Borrelia burgdorferi</i> sensu latotickwild rodent |
| spellingShingle | Seong Yoon Kim Tae-Kyu Kim Tae Yun Kim Hee Il Lee Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea Pathogens lyme disease <i>Borrelia burgdorferi</i> sensu lato tick wild rodent |
| title | Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea |
| title_full | Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea |
| title_fullStr | Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea |
| title_full_unstemmed | Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea |
| title_short | Geographical Distribution of <i>Borrelia burgdorferi</i> sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea |
| title_sort | geographical distribution of i borrelia burgdorferi i sensu lato in ticks collected from wild rodents in the republic of korea |
| topic | lyme disease <i>Borrelia burgdorferi</i> sensu lato tick wild rodent |
| url | https://www.mdpi.com/2076-0817/9/11/866 |
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