Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis.
<h4>Purpose</h4>The aim of this review was to (1) characterize the time-course of markers of exercise-induced muscle damage (EIMD) based on the level of maximal voluntary contraction torque loss at 24-48h post-exercise (MVCloss24-48h), (2) identify factors (e.g., exercise and population...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0271233 |
| _version_ | 1828190735485108224 |
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| author | Emeric Chalchat Anne-Fleur Gaston Keyne Charlot Luis Peñailillo Omar Valdés Pierre-Emmanuel Tardo-Dino Kazunori Nosaka Vincent Martin Sebastian Garcia-Vicencio Julien Siracusa |
| author_facet | Emeric Chalchat Anne-Fleur Gaston Keyne Charlot Luis Peñailillo Omar Valdés Pierre-Emmanuel Tardo-Dino Kazunori Nosaka Vincent Martin Sebastian Garcia-Vicencio Julien Siracusa |
| author_sort | Emeric Chalchat |
| collection | DOAJ |
| description | <h4>Purpose</h4>The aim of this review was to (1) characterize the time-course of markers of exercise-induced muscle damage (EIMD) based on the level of maximal voluntary contraction torque loss at 24-48h post-exercise (MVCloss24-48h), (2) identify factors (e.g., exercise and population characteristics) affecting the level of MVCloss24-48h, and (3) evaluate the appropriateness of EIMD markers as indicators of MVCloss24-48h.<h4>Methods</h4>Magnitude of change of each EIMD markers was normalized using the standardized mean differences method to compare the results from different studies. Time-course of EIMD markers were characterized according to three levels of MVCloss24-48h based on a clustering analysis of the 141 studies included. Association between MVCloss24-48h levels and participant´s characteristics or exercise type/modalities were assessed. Meta-regressions were performed to investigate the associations between MVCloss24-48h and EIMD markers changes at <6h, 24h, 48h, 72h and >96h after exercise.<h4>Results</h4>Time-course of EIMD markers recovery differs between levels of MVCloss24-48h. Training status and exercise type/modality were associated with MVCloss24-48h level (p<0.05). MVCloss24-48h was correlated to changes in myoglobin concentration (<6h), jump height (24h) and range of motion (48h) (p<0.001).<h4>Conclusion</h4>As the exercise could differently affect markers as function of the EIMD severity (i.e., MVCloss24-48h levels), different markers should be used as function of the timing of measurement. Mb concentration should be used during the first hours after the exercise (<6h), whereas jump height (24h) and range of motion (48h) could be used as surrogate for maximal voluntary contraction later. Moreover, training status and exercise type/modality could influence the magnitude of MVCloss24-48h. |
| first_indexed | 2024-04-12T08:26:44Z |
| format | Article |
| id | doaj.art-cb5c02621dd1440184f2d12b4147a588 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T08:26:44Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-cb5c02621dd1440184f2d12b4147a5882022-12-22T03:40:21ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01177e027123310.1371/journal.pone.0271233Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis.Emeric ChalchatAnne-Fleur GastonKeyne CharlotLuis PeñaililloOmar ValdésPierre-Emmanuel Tardo-DinoKazunori NosakaVincent MartinSebastian Garcia-VicencioJulien Siracusa<h4>Purpose</h4>The aim of this review was to (1) characterize the time-course of markers of exercise-induced muscle damage (EIMD) based on the level of maximal voluntary contraction torque loss at 24-48h post-exercise (MVCloss24-48h), (2) identify factors (e.g., exercise and population characteristics) affecting the level of MVCloss24-48h, and (3) evaluate the appropriateness of EIMD markers as indicators of MVCloss24-48h.<h4>Methods</h4>Magnitude of change of each EIMD markers was normalized using the standardized mean differences method to compare the results from different studies. Time-course of EIMD markers were characterized according to three levels of MVCloss24-48h based on a clustering analysis of the 141 studies included. Association between MVCloss24-48h levels and participant´s characteristics or exercise type/modalities were assessed. Meta-regressions were performed to investigate the associations between MVCloss24-48h and EIMD markers changes at <6h, 24h, 48h, 72h and >96h after exercise.<h4>Results</h4>Time-course of EIMD markers recovery differs between levels of MVCloss24-48h. Training status and exercise type/modality were associated with MVCloss24-48h level (p<0.05). MVCloss24-48h was correlated to changes in myoglobin concentration (<6h), jump height (24h) and range of motion (48h) (p<0.001).<h4>Conclusion</h4>As the exercise could differently affect markers as function of the EIMD severity (i.e., MVCloss24-48h levels), different markers should be used as function of the timing of measurement. Mb concentration should be used during the first hours after the exercise (<6h), whereas jump height (24h) and range of motion (48h) could be used as surrogate for maximal voluntary contraction later. Moreover, training status and exercise type/modality could influence the magnitude of MVCloss24-48h.https://doi.org/10.1371/journal.pone.0271233 |
| spellingShingle | Emeric Chalchat Anne-Fleur Gaston Keyne Charlot Luis Peñailillo Omar Valdés Pierre-Emmanuel Tardo-Dino Kazunori Nosaka Vincent Martin Sebastian Garcia-Vicencio Julien Siracusa Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. PLoS ONE |
| title | Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. |
| title_full | Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. |
| title_fullStr | Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. |
| title_full_unstemmed | Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. |
| title_short | Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis. |
| title_sort | appropriateness of indirect markers of muscle damage following lower limbs eccentric biased exercises a systematic review with meta analysis |
| url | https://doi.org/10.1371/journal.pone.0271233 |
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