Development of a Validated UPLC-MS/MS Method for Analyzing Major Ginseng Saponins from Various Ginseng Species

Development of a Validated UPLC-MS/MS Method for Analyzing Major Ginseng Saponins from Various Ginseng Species

Ginsenosides, which contain one triterpene and one or more sugar moieties, are the major bioactive compounds of ginseng. The aim of this study was to develop and optimize a specific and reliable ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the analysis of...

Full description

Bibliographic Details
Main Authors:	Ling Yang, Chi-Lin Li, Yung-Yi Cheng, Tung-Hu Tsai
Format:	Article
Language:	English
Published:	MDPI AG 2019-11-01
Series:	Molecules
Subjects:	ginseng species ginsenosides traditional chinese medicine ultra-performance liquid chromatography-tandem mass spectrometry
Online Access:	https://www.mdpi.com/1420-3049/24/22/4065

Similar Items

Analysis of Ginsenoside in Red Ginseng and Its Metabolism in Type 2 Diabetic Rats by UPLC-MS
by: WANG He-yu, et al.
Published: (2021-11-01)

Chemical diversity of ginseng saponins from Panax ginseng
by: Byong-Kyu Shin, et al.
Published: (2015-10-01)

UPLC-QqQ-MS/MS-based Quantitative Analysis on Bile Acid in Hyperthyroidism Rats to Explore the Effects of Ginseng Herbs
by: LIU Lin-lin, et al.
Published: (2023-07-01)

Comprehensive Profiling and Quantification of Ginsenosides in the Root, Stem, Leaf, and Berry of Panax ginseng by UPLC-QTOF/MS
by: Jae Won Lee, et al.
Published: (2017-12-01)

Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng
by: Jeong HS, et al.
Published: (2010-03-01)

Rapid separation and identification of 31 major saponins in Shizhu ginseng by ultra-high performance liquid chromatography–electron spray ionization–MS/MS
by: Ting-Ting Sun, et al.
Published: (2016-07-01)

UPLC-QTOF/MS-Based Metabolomics Applied for the Quality Evaluation of Four Processed Panax ginseng Products
by: Jae Won Lee, et al.
Published: (2018-08-01)

Determination of 46 Ginsenosides in Different Processed Ginseng Products by Dispersive Solid Phase Extraction Combined with Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry
by: WANG Yanhong, WU Yutong, CAO Hongfang, XU Xuanwei, ZHAO Dan, LI Yueru
Published: (2023-09-01)

Effects of steaming on saponin compositions and antiproliferative activity of Vietnamese ginseng
by: Thi Hong Van Le, et al.
Published: (2015-07-01)

Component analysis of cultivated ginseng and mountain ginseng to the change of ginsenoside components in the process of heating and fermentation
by: Bae -Cheon Cha, et al.
Published: (2010-06-01)

Pharmacokinetics of Schizandrin and Its Pharmaceutical Products Assessed Using a Validated LC–MS/MS Method
by: Chi-Lin Li, et al.
Published: (2018-01-01)

Panax ginseng
by: Alyaa Majid
Published: (2019-05-01)

Panax ginseng
by: Alyaa Majid
Published: (2019-05-01)

The Uroprotective Efficacy of Total Ginsenosides in Chinese Ginseng on Chemotherapy with Cyclophosphamide
by: Yung-Hsiang Chen, et al.
Published: (2022-08-01)

Component Analysis of Ginseng Ice Wine by GC-MS and LC-MS
by: WU Yong-xi, et al.
Published: (2022-03-01)

A Comparative Study on Analysis of Ginsenosides in American Ginseng Root Residue by HPLC-DAD-ESI-MS and UPLC-HRMS-MS/MS
by: Bo-Yang Hsu, et al.
Published: (2022-05-01)

Ginsenosides analysis of New Zealand–grown forest Panax ginseng by LC-QTOF-MS/MS
by: Wei Chen, et al.
Published: (2020-07-01)

High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS
by: Maria Blomqvist, et al.
Published: (2017-07-01)

Modification of ginsenoside composition in red ginseng (Panax ginseng) by ultrasonication
by: Sung-hyun Yoon, et al.
Published: (2016-07-01)

Ginseng and obesity
by: Zhipeng Li, et al.
Published: (2018-01-01)

Structural Identification of Ginsenoside Based on UPLC-QTOF-MS of Black Ginseng (<i>Panax Ginseng</i> C.A. Mayer)
by: Hyo-Bin Oh, et al.
Published: (2024-01-01)

Ginsenoside Absorption Rate and Extent Enhancement of Black Ginseng (CJ EnerG) over Red Ginseng in Healthy Adults
by: Saebyul Yoo, et al.
Published: (2021-04-01)

Advances in Saponin Diversity of <i>Panax ginseng</i>
by: Xiangmin Piao, et al.
Published: (2020-07-01)

Saponins of ginseng products: a review of their transformation in processing
by: Xian-Wen Ye, et al.
Published: (2023-04-01)

Black Ginseng and Its Saponins: Preparation, Phytochemistry and Pharmacological Effects
by: Ahmed M. Metwaly, et al.
Published: (2019-05-01)

Panax ginseng – A review
by: Alyaa Majid
Published: (2019-05-01)

Bacterial endophytes from ginseng and their biotechnological application
by: Luan Luong Chu, et al.
Published: (2022-01-01)

Determination of chloramphenicol antibiotics and their metabolite in soil by UPLC-MS/MS
by: Xulei MI, et al.
Published: (2023-04-01)

Comparison of Ginsenoside Components of Various Tissues of New Zealand Forest-Grown Asian Ginseng (<i>Panax Ginseng</i>) and American Ginseng (<i>Panax Quinquefolium</i> L.)
by: Wei Chen, et al.
Published: (2020-02-01)

Neuroprotective Effects of Red Ginseng Saponins in Scopolamine-Treated Rats and Activity Screening Based on Pharmacokinetics
by: Jianbo Chen, et al.
Published: (2019-06-01)

Pharmacological potential of ginseng and its major component ginsenosides
by: Zubair Ahmed Ratan, et al.
Published: (2021-03-01)

Quick and Sensitive UPLC-ESI-MS/MS Method for Simultaneous Estimation of Sofosbuvir and Its Metabolite in Human Plasma
by: Mohammad H. Semreen, et al.
Published: (2019-04-01)

A Review of Neuroprotective Effects and Mechanisms of Ginsenosides From Panax Ginseng in Treating Ischemic Stroke
by: Aimei Zhao, et al.
Published: (2022-07-01)

Panax Ginseng in the treatment of Alzheimer's disease and vascular dementia
by: Zhiyong Wang, et al.
Published: (2023-07-01)

Ginsenoside Rg12, a new dammarane-type triterpene saponin from Panax ginseng root
by: Dong Gu Lee, et al.
Published: (2017-10-01)

Discrepancy Study of the Chemical Constituents of Panax Ginseng from Different Growth Environments with UPLC-MS-Based Metabolomics Strategy
by: Yizheng Sun, et al.
Published: (2023-03-01)

Characterization of Ginsenosides from the Root of <i>Panax ginseng</i> by Integrating Untargeted Metabolites Using UPLC-Triple TOF-MS
by: Yizheng Sun, et al.
Published: (2023-02-01)

Development of a Novel UPLC-MS/MS Method for the Simultaneous Determination of 16 Mycotoxins in Different Tea Categories
by: Haiyan Zhou, et al.
Published: (2022-02-01)

The interaction between ginseng and gut microbiota
by: Linxian Zhao, et al.
Published: (2023-11-01)

Comparative analysis of physicochemical properties, ginsenosides content and α-amylase inhibitory effects in white ginseng and red ginseng
by: Huairui Wang, et al.
Published: (2023-01-01)