Brain tuberculoma in a non-endemic area

Brain tuberculoma has previously accounted for up to a third of new intracranial lesions in areas endemic with tuberculosis, but is unexpected in the United States and other Western countries with improved disease control. Here we show the importance of considering this diagnosis in at-risk patients...

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Main Authors: Robert M. Lober, Anand Veeravagu, Harminder Singh
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Infectious Disease Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/idr/article/view/4147
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author Robert M. Lober
Anand Veeravagu
Harminder Singh
author_facet Robert M. Lober
Anand Veeravagu
Harminder Singh
author_sort Robert M. Lober
collection DOAJ
description Brain tuberculoma has previously accounted for up to a third of new intracranial lesions in areas endemic with tuberculosis, but is unexpected in the United States and other Western countries with improved disease control. Here we show the importance of considering this diagnosis in at-risk patients, even with no definitive pulmonary involvement. We describe a young man who presented with partial seizures and underwent craniotomy for resection of a frontoparietal tuberculoma. He subsequently completed six months of antituberculosis therapy and was doing well without neurological sequelae or evidence of recurrence five months after completion of therapy. With resurgence of tuberculosis cases in the United States and other Western countries, intracerebral tuberculoma should remain a diagnostic consideration in at-risk patients with new space occupying lesions. Mass lesions causing neurological sequelae can be safely addressed surgically and followed with antituberculosis therapy.
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spelling doaj.art-cb669e3ff0ae4c848a15b8166026b2f32022-12-21T20:25:22ZengMDPI AGInfectious Disease Reports2036-74302036-74492013-01-0151e1e110.4081/idr.2013.e12396Brain tuberculoma in a non-endemic areaRobert M. Lober0Anand Veeravagu1Harminder Singh2Department of Neurosurgery, Stanford Hospitals and Clinics, Stanford, CADepartment of Neurosurgery, Stanford Hospitals and Clinics, Stanford, CADepartment of Neurosurgery, Stanford Hospitals and Clinics, Stanford, CABrain tuberculoma has previously accounted for up to a third of new intracranial lesions in areas endemic with tuberculosis, but is unexpected in the United States and other Western countries with improved disease control. Here we show the importance of considering this diagnosis in at-risk patients, even with no definitive pulmonary involvement. We describe a young man who presented with partial seizures and underwent craniotomy for resection of a frontoparietal tuberculoma. He subsequently completed six months of antituberculosis therapy and was doing well without neurological sequelae or evidence of recurrence five months after completion of therapy. With resurgence of tuberculosis cases in the United States and other Western countries, intracerebral tuberculoma should remain a diagnostic consideration in at-risk patients with new space occupying lesions. Mass lesions causing neurological sequelae can be safely addressed surgically and followed with antituberculosis therapy.http://www.pagepress.org/journals/index.php/idr/article/view/4147tuberculoma, tuberculosis, anti-tuberculous therapy
spellingShingle Robert M. Lober
Anand Veeravagu
Harminder Singh
Brain tuberculoma in a non-endemic area
Infectious Disease Reports
tuberculoma, tuberculosis, anti-tuberculous therapy
title Brain tuberculoma in a non-endemic area
title_full Brain tuberculoma in a non-endemic area
title_fullStr Brain tuberculoma in a non-endemic area
title_full_unstemmed Brain tuberculoma in a non-endemic area
title_short Brain tuberculoma in a non-endemic area
title_sort brain tuberculoma in a non endemic area
topic tuberculoma, tuberculosis, anti-tuberculous therapy
url http://www.pagepress.org/journals/index.php/idr/article/view/4147
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