Myelin-phagocytosing macrophages modulate autoreactive T cell proliferation
<p>Abstract</p> <p>Introduction</p> <p>Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS) in which macrophages play a central role. Initially, macrophages where thought to be merely detrimental in MS, however, r...
Main Authors: | Hellings Niels, Stinissen Piet, Bogie Jeroen FJ, Hendriks Jerome JA |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
|
Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/8/1/85 |
Similar Items
-
Myelin-derived lipids modulate macrophage activity by liver X receptor activation.
by: Jeroen F J Bogie, et al.
Published: (2012-01-01) -
Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis
by: Elien Wouters, et al.
Published: (2020-12-01) -
Treg-Resistant Cytotoxic CD4<sup>+</sup> T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation
by: Cindy Hoeks, et al.
Published: (2021-05-01) -
Human Wharton's Jelly-Derived Stem Cells Display Immunomodulatory Properties and Transiently Improve Rat Experimental Autoimmune Encephalomyelitis
by: Raf Donders, et al.
Published: (2015-10-01) -
Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis
by: Hongcheng Yang, et al.
Published: (2019-08-01)