Development of a quantitative methylation-specific droplet digital PCR assay for detecting Dickkopf-related protein 3

Development of a quantitative methylation-specific droplet digital PCR assay for detecting Dickkopf-related protein 3

Abstract Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression. The methylation status of the Dickkopf-related protein 3 (DKK3) promoter region is correlated with the metastasis and recu...

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Bibliographic Details
Main Authors: Kenji Araki, Ai Kurosawa, Hiromi Kumon
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Research Notes
Subjects:
Dickkopf-related protein 3
Methylation
Liquid biopsy
Droplet digital polymerase chain reaction
Online Access:https://doi.org/10.1186/s13104-022-06056-6

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