A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application
Postbiotics are innovative tools in animal husbandry, providing eco-friendly solutions for disease management within the industry. In this study, a new postbiotic product was evaluated for its impact on the health of rainbow trout (<i>Oncorhynchus mykiss</i>). In vivo studies were conduc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/14/5/744 |
| _version_ | 1797264942030651392 |
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| author | Mario Quintanilla-Pineda Francisco C. Ibañez Chajira Garrote-Achou Florencio Marzo |
| author_facet | Mario Quintanilla-Pineda Francisco C. Ibañez Chajira Garrote-Achou Florencio Marzo |
| author_sort | Mario Quintanilla-Pineda |
| collection | DOAJ |
| description | Postbiotics are innovative tools in animal husbandry, providing eco-friendly solutions for disease management within the industry. In this study, a new postbiotic product was evaluated for its impact on the health of rainbow trout (<i>Oncorhynchus mykiss</i>). In vivo studies were conducted to assess the safety of the <i>Weissella cibaria</i> strains used in postbiotic production. Additionally, this study evaluated the impact of diet supplementation with 0.50% postbiotics on growth performance during a 30-day feeding trial; the gut microbial communities, immunomodulation, and protection against <i>Yersinia ruckeri</i> infection were evaluated. The strains did not harm the animals during the 20-day observation period. Furthermore, the effect of postbiotics on growth performance was not significant (<i>p</i> < 0.05). The treated group showed a significant increase in acid-lactic bacteria on the 30th day of the feeding trial, with counts of 3.42 ± 0.21 log CFU/mL. Additionally, there was an up-regulation of the pro-inflammatory cytokine <i>IL-1β</i> in head kidney samples after 48 h of feed supplementation, whereas cytokines <i>IL-10</i>, <i>IL-8, INF-γ</i>, and <i>TNF-α</i> were down-regulated. The findings indicate that rainbow trout fed with postbiotics saw an improvement in their survival rate against <i>Y. ruckeri</i>, with a 20.66% survival improvement in the treated group. This study proves that incorporating postbiotics from two strains of <i>W. cibaria</i> previously isolated from rainbow trout into the diet of fish has immunomodulatory effects, enhances intestinal microbial composition, and improves fish resistance against <i>Y. ruckeri.</i> |
| first_indexed | 2024-04-25T00:36:54Z |
| format | Article |
| id | doaj.art-cb6a825e923a43dfb6079f71a86137a3 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-04-25T00:36:54Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-cb6a825e923a43dfb6079f71a86137a32024-03-12T16:38:08ZengMDPI AGAnimals2076-26152024-02-0114574410.3390/ani14050744A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture ApplicationMario Quintanilla-Pineda0Francisco C. Ibañez1Chajira Garrote-Achou2Florencio Marzo3Laboratorio de Fisiología y Nutrición Animal, Universidad Pública de Navarra, 31006 Pamplona, SpainLaboratorio de Fisiología y Nutrición Animal, Universidad Pública de Navarra, 31006 Pamplona, SpainPENTABIOL SL, 31191 Pamplona, SpainLaboratorio de Fisiología y Nutrición Animal, Universidad Pública de Navarra, 31006 Pamplona, SpainPostbiotics are innovative tools in animal husbandry, providing eco-friendly solutions for disease management within the industry. In this study, a new postbiotic product was evaluated for its impact on the health of rainbow trout (<i>Oncorhynchus mykiss</i>). In vivo studies were conducted to assess the safety of the <i>Weissella cibaria</i> strains used in postbiotic production. Additionally, this study evaluated the impact of diet supplementation with 0.50% postbiotics on growth performance during a 30-day feeding trial; the gut microbial communities, immunomodulation, and protection against <i>Yersinia ruckeri</i> infection were evaluated. The strains did not harm the animals during the 20-day observation period. Furthermore, the effect of postbiotics on growth performance was not significant (<i>p</i> < 0.05). The treated group showed a significant increase in acid-lactic bacteria on the 30th day of the feeding trial, with counts of 3.42 ± 0.21 log CFU/mL. Additionally, there was an up-regulation of the pro-inflammatory cytokine <i>IL-1β</i> in head kidney samples after 48 h of feed supplementation, whereas cytokines <i>IL-10</i>, <i>IL-8, INF-γ</i>, and <i>TNF-α</i> were down-regulated. The findings indicate that rainbow trout fed with postbiotics saw an improvement in their survival rate against <i>Y. ruckeri</i>, with a 20.66% survival improvement in the treated group. This study proves that incorporating postbiotics from two strains of <i>W. cibaria</i> previously isolated from rainbow trout into the diet of fish has immunomodulatory effects, enhances intestinal microbial composition, and improves fish resistance against <i>Y. ruckeri.</i>https://www.mdpi.com/2076-2615/14/5/744immunomodulationsalmonidsacid-lactic bacteriamicrobiota modulationgrowth performanceRed Mouth Disease |
| spellingShingle | Mario Quintanilla-Pineda Francisco C. Ibañez Chajira Garrote-Achou Florencio Marzo A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application Animals immunomodulation salmonids acid-lactic bacteria microbiota modulation growth performance Red Mouth Disease |
| title | A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application |
| title_full | A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application |
| title_fullStr | A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application |
| title_full_unstemmed | A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application |
| title_short | A Novel Postbiotic Product Based on <i>Weissella cibaria</i> for Enhancing Disease Resistance in Rainbow Trout: Aquaculture Application |
| title_sort | novel postbiotic product based on i weissella cibaria i for enhancing disease resistance in rainbow trout aquaculture application |
| topic | immunomodulation salmonids acid-lactic bacteria microbiota modulation growth performance Red Mouth Disease |
| url | https://www.mdpi.com/2076-2615/14/5/744 |
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