Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation

Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins....

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Main Authors: Sunil Vitthalrao Jagtap, Suresh J. Bhosale, P.G.Chougule, Shrutika D Dhawan, Dhiraj Shukla
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-07-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6218/12794_CE(Ra1)_F(GH)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf
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author Sunil Vitthalrao Jagtap
Suresh J. Bhosale
P.G.Chougule
Shrutika D Dhawan
Dhiraj Shukla
author_facet Sunil Vitthalrao Jagtap
Suresh J. Bhosale
P.G.Chougule
Shrutika D Dhawan
Dhiraj Shukla
author_sort Sunil Vitthalrao Jagtap
collection DOAJ
description Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins. Fine needle aspiration cytology was positive for duct carcinoma cells. Histo pathologic examination, reported as “Multicentric infiltrating duct carcinoma with squamous differentiation left breast”, grade 2. Immunohistochemistry revealed negativity for ER, PR and positivity for HER-2/neu. We are presenting this rare case for clinical, radiological, histopathological and immunohistochemical study.
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spelling doaj.art-cb6b6eac35594c5492dced693bd943792022-12-21T19:05:21ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-07-0197ED09ED1010.7860/JCDR/2015/12794.6218Multicentric Metaplastic Breast Carcinoma with Squamous DifferentiationSunil Vitthalrao Jagtap0Suresh J. Bhosale1P.G.Chougule2Shrutika D Dhawan3Dhiraj Shukla4Professor, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.Professor, Department of Surgery, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.Professor, Department of Surgery, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.Assistant Lecturer, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.Assistant Lecturer, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins. Fine needle aspiration cytology was positive for duct carcinoma cells. Histo pathologic examination, reported as “Multicentric infiltrating duct carcinoma with squamous differentiation left breast”, grade 2. Immunohistochemistry revealed negativity for ER, PR and positivity for HER-2/neu. We are presenting this rare case for clinical, radiological, histopathological and immunohistochemical study.https://jcdr.net/articles/PDF/6218/12794_CE(Ra1)_F(GH)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdfhistological subtypeuncommon breast malignancies
spellingShingle Sunil Vitthalrao Jagtap
Suresh J. Bhosale
P.G.Chougule
Shrutika D Dhawan
Dhiraj Shukla
Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
Journal of Clinical and Diagnostic Research
histological subtype
uncommon breast malignancies
title Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
title_full Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
title_fullStr Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
title_full_unstemmed Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
title_short Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
title_sort multicentric metaplastic breast carcinoma with squamous differentiation
topic histological subtype
uncommon breast malignancies
url https://jcdr.net/articles/PDF/6218/12794_CE(Ra1)_F(GH)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf
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AT shrutikaddhawan multicentricmetaplasticbreastcarcinomawithsquamousdifferentiation
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