The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study

Introduction Multiple abortions are consistently associated with adverse health consequences. Prior abortion is a known risk factor for another abortion. Objective To determine the persistence of the association of a first-pregnancy abortion with the likelihood of subsequent pregnancy outcomes. Meth...

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Main Authors: James Studnicki, Tessa Longbons, David C. Reardon, John W. Fisher, Donna J. Harrison, Ingrid Skop, Christina A. Cirucci, Christopher Craver, Maka Tsulukidze, Zbigniew Ras
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Health Services Research & Managerial Epidemiology
Online Access:https://doi.org/10.1177/23333928221130942
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author James Studnicki
Tessa Longbons
David C. Reardon
John W. Fisher
Donna J. Harrison
Ingrid Skop
Christina A. Cirucci
Christopher Craver
Maka Tsulukidze
Zbigniew Ras
author_facet James Studnicki
Tessa Longbons
David C. Reardon
John W. Fisher
Donna J. Harrison
Ingrid Skop
Christina A. Cirucci
Christopher Craver
Maka Tsulukidze
Zbigniew Ras
author_sort James Studnicki
collection DOAJ
description Introduction Multiple abortions are consistently associated with adverse health consequences. Prior abortion is a known risk factor for another abortion. Objective To determine the persistence of the association of a first-pregnancy abortion with the likelihood of subsequent pregnancy outcomes. Methods Data was extracted for a study population of 5453 continuously eligible Medicaid beneficiaries in states which funded and reported elective abortions 1999–2015. Women age 16 in 1999 were organized into three cohorts based upon the first pregnancy outcome: abortion, birth, natural loss. Results Women in the abortion cohort are more likely than those in the birth cohort to experience another abortion rather than a birth or natural loss, and less likely to experience a live birth rather than an abortion or natural loss, for every subsequent pregnancy. The tendency toward abortion (OR 2.99, CL 2.02-4.43) and away from birth (OR 0.49, CL 0.39-0.63) peaks at the sixth pregnancy, but persists throughout the reproductive period ages 16–32. The pattern is reversed, but similarly consistent, for women in the birth cohort. They remain likelier to have another birth rather than an abortion or natural loss in subsequent pregnancies. Compared to the birth cohort, the abortion cohort had 1.35 times as many pregnancies: 4.31 times the abortions, 1.53 times the natural losses, but only 0.52 times the births. They were 4.3 and 5.0 times as likely to have 2-plus and 3-plus abortions, but only 0.47 times and 0.31 times as likely to have 2-plus and 3-plus births. Of the abortion cohort, 37.1% had no births. By contrast, 73.6% of the birth cohort had no abortions. Conclusion The first-pregnancy abortion maintains a strong and persistent association with the likelihood of another abortion in subsequent pregnancies, enabling a cascade of adverse events associated with multiple abortions.
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spelling doaj.art-cb6c09a5ee3b44dba897a77e651ba7202022-12-22T04:30:14ZengSAGE PublishingHealth Services Research & Managerial Epidemiology2333-39282022-10-01910.1177/23333928221130942The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort StudyJames Studnicki0Tessa Longbons1David C. Reardon2John W. Fisher3Donna J. Harrison4Ingrid Skop5Christina A. Cirucci6Christopher Craver7Maka Tsulukidze8Zbigniew Ras9 , Arlington, VA, USA , Arlington, VA, USA Elliot Institute, Springfield, IL, USA , Arlington, VA, USA American Association of Pro-Life Obstetricians and Gynecologists, Eau Claire, MI, USA , Arlington, VA, USA , Arlington, VA, USA , Arlington, VA, USA Department of Health Sciences, , Fort Myers, FL, USA Computer Science Department, , Charlotte, NC, USAIntroduction Multiple abortions are consistently associated with adverse health consequences. Prior abortion is a known risk factor for another abortion. Objective To determine the persistence of the association of a first-pregnancy abortion with the likelihood of subsequent pregnancy outcomes. Methods Data was extracted for a study population of 5453 continuously eligible Medicaid beneficiaries in states which funded and reported elective abortions 1999–2015. Women age 16 in 1999 were organized into three cohorts based upon the first pregnancy outcome: abortion, birth, natural loss. Results Women in the abortion cohort are more likely than those in the birth cohort to experience another abortion rather than a birth or natural loss, and less likely to experience a live birth rather than an abortion or natural loss, for every subsequent pregnancy. The tendency toward abortion (OR 2.99, CL 2.02-4.43) and away from birth (OR 0.49, CL 0.39-0.63) peaks at the sixth pregnancy, but persists throughout the reproductive period ages 16–32. The pattern is reversed, but similarly consistent, for women in the birth cohort. They remain likelier to have another birth rather than an abortion or natural loss in subsequent pregnancies. Compared to the birth cohort, the abortion cohort had 1.35 times as many pregnancies: 4.31 times the abortions, 1.53 times the natural losses, but only 0.52 times the births. They were 4.3 and 5.0 times as likely to have 2-plus and 3-plus abortions, but only 0.47 times and 0.31 times as likely to have 2-plus and 3-plus births. Of the abortion cohort, 37.1% had no births. By contrast, 73.6% of the birth cohort had no abortions. Conclusion The first-pregnancy abortion maintains a strong and persistent association with the likelihood of another abortion in subsequent pregnancies, enabling a cascade of adverse events associated with multiple abortions.https://doi.org/10.1177/23333928221130942
spellingShingle James Studnicki
Tessa Longbons
David C. Reardon
John W. Fisher
Donna J. Harrison
Ingrid Skop
Christina A. Cirucci
Christopher Craver
Maka Tsulukidze
Zbigniew Ras
The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
Health Services Research & Managerial Epidemiology
title The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
title_full The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
title_fullStr The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
title_full_unstemmed The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
title_short The Enduring Association of a First Pregnancy Abortion with Subsequent Pregnancy Outcomes: A Longitudinal Cohort Study
title_sort enduring association of a first pregnancy abortion with subsequent pregnancy outcomes a longitudinal cohort study
url https://doi.org/10.1177/23333928221130942
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