DISC1 and reelin interact to alter cognition, inhibition, and neurogenesis in a novel mouse model of schizophrenia

DISC1 and reelin interact to alter cognition, inhibition, and neurogenesis in a novel mouse model of schizophrenia

The etiology of schizophrenia (SCZ) is multifactorial, and depending on a host of genetic and environmental factors. Two putative SCZ susceptibility genes, Disrupted-in-Schizophrenia-1 (DISC1) and reelin (RELN), interact at a molecular level, suggesting that combined disruption of both may lead to a...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Heather L. Mahoney, Charissa A. Bloom, Hannah S. Justin, Bianca M. Capraro, Christopher Morris, David Gonzalez, Emily Sandefur, John Faulkner, Samantha Reiss, Angel Valladares, Angie Ocampo, Bethany Carter, April L. Lussier, Linh Phuong Dinh, Edwin Weeber, Joshua Gamsby, Danielle Gulick
Format: Artykuł
Język:English
Wydane: Frontiers Media S.A. 2024-01-01
Seria:Frontiers in Cellular Neuroscience
Hasła przedmiotowe:
schizophrenia
DISC1
reelin
neurogenesis
mouse model
cognition
Dostęp online:https://www.frontiersin.org/articles/10.3389/fncel.2023.1321632/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1321632/full

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