Screening E3 substrates using a live phage display library.

Screening E3 substrates using a live phage display library.

Ubiquitin ligases (E3s) determine specificity of ubiquitination by recognizing target substrates. However, most of their substrates are unknown. Most known substrates have been identified using distinct approaches in different laboratories. We developed a high-throughput strategy using a live phage...

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Bibliographic Details
Main Authors: Zhengguang Guo, Xiaorong Wang, Huihua Li, Youhe Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790729?pdf=render

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