Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis
Abstract Background We discuss the safety, since their introduction, of phakic intraocular lenses (pIOLs) to correct refractive errors in healthy eyes. We investigated the reasons for pIOL explantation and the associated perioperative complications. Methods This retrospective, cross-sectional study...
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| Format: | Article |
| Language: | English |
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BMC
2021-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-021-01847-0 |
| _version_ | 1818458992025796608 |
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| author | Timur M. Yildirim Ramin Khoramnia Hyeck-Soo Son Christian S. Mayer Grzegorz Łabuz Donald J. Munro Gerd U. Auffarth |
| author_facet | Timur M. Yildirim Ramin Khoramnia Hyeck-Soo Son Christian S. Mayer Grzegorz Łabuz Donald J. Munro Gerd U. Auffarth |
| author_sort | Timur M. Yildirim |
| collection | DOAJ |
| description | Abstract Background We discuss the safety, since their introduction, of phakic intraocular lenses (pIOLs) to correct refractive errors in healthy eyes. We investigated the reasons for pIOL explantation and the associated perioperative complications. Methods This retrospective, cross-sectional study included 69 pIOLs, explanted at a single tertiary center between July 2005 and March 2020: 34 angle-supported (G1), 28 iris-fixated (G2) and seven posterior chamber (G3) pIOLs. Case data including the reason for explantation was taken from the patient records. Intra- and postoperative complications were evaluated for an association with the pIOL. Results The mean duration in the eye was 10.4 (0.2–28) years. Cataractogenesis and subsequent surgery that required pIOL explantation was the reason in 42% of all cases. In 22%, cataract in combination with endothelial damage prompted explantation, with 26, 18 and 14% for G1, G2 and G3 respectively. The second most common reasons were corneal damage alone in the angle-supported group (26%), IOL subluxation in the iris-fixated group (18%), and photopic disturbance in the posterior chamber group (29%). In 68% of all explantations, the surgical course was unremarkable, while in the remaining cases perioperative complications were associated with the lens in 45.7%. Conclusion Overall, the need for cataract surgery was the most common reason for pIOL explantation. Corneal complications were more frequent in the angle-supported pIOLs and their removal was associated with higher rates of complication compared to the other groups. |
| first_indexed | 2024-12-14T23:07:16Z |
| format | Article |
| id | doaj.art-cb6ec7d479524246bcc27f35d43e1fef |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-14T23:07:16Z |
| publishDate | 2021-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-cb6ec7d479524246bcc27f35d43e1fef2022-12-21T22:44:17ZengBMCBMC Ophthalmology1471-24152021-02-012111910.1186/s12886-021-01847-0Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysisTimur M. Yildirim0Ramin Khoramnia1Hyeck-Soo Son2Christian S. Mayer3Grzegorz Łabuz4Donald J. Munro5Gerd U. Auffarth6The David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergThe David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of HeidelbergAbstract Background We discuss the safety, since their introduction, of phakic intraocular lenses (pIOLs) to correct refractive errors in healthy eyes. We investigated the reasons for pIOL explantation and the associated perioperative complications. Methods This retrospective, cross-sectional study included 69 pIOLs, explanted at a single tertiary center between July 2005 and March 2020: 34 angle-supported (G1), 28 iris-fixated (G2) and seven posterior chamber (G3) pIOLs. Case data including the reason for explantation was taken from the patient records. Intra- and postoperative complications were evaluated for an association with the pIOL. Results The mean duration in the eye was 10.4 (0.2–28) years. Cataractogenesis and subsequent surgery that required pIOL explantation was the reason in 42% of all cases. In 22%, cataract in combination with endothelial damage prompted explantation, with 26, 18 and 14% for G1, G2 and G3 respectively. The second most common reasons were corneal damage alone in the angle-supported group (26%), IOL subluxation in the iris-fixated group (18%), and photopic disturbance in the posterior chamber group (29%). In 68% of all explantations, the surgical course was unremarkable, while in the remaining cases perioperative complications were associated with the lens in 45.7%. Conclusion Overall, the need for cataract surgery was the most common reason for pIOL explantation. Corneal complications were more frequent in the angle-supported pIOLs and their removal was associated with higher rates of complication compared to the other groups.https://doi.org/10.1186/s12886-021-01847-0Complications of refractive surgeryIOL registryIOL designIris-clawICLAngle-supported |
| spellingShingle | Timur M. Yildirim Ramin Khoramnia Hyeck-Soo Son Christian S. Mayer Grzegorz Łabuz Donald J. Munro Gerd U. Auffarth Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis BMC Ophthalmology Complications of refractive surgery IOL registry IOL design Iris-claw ICL Angle-supported |
| title | Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis |
| title_full | Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis |
| title_fullStr | Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis |
| title_full_unstemmed | Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis |
| title_short | Reasons for explantation of phakic intraocular lenses and associated perioperative complications: cross-sectional explant registry analysis |
| title_sort | reasons for explantation of phakic intraocular lenses and associated perioperative complications cross sectional explant registry analysis |
| topic | Complications of refractive surgery IOL registry IOL design Iris-claw ICL Angle-supported |
| url | https://doi.org/10.1186/s12886-021-01847-0 |
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