Nanomaterials targeting iron homeostasis: a promising strategy for cancer treatment

Nanomaterials targeting iron homeostasis: a promising strategy for cancer treatment

Iron is essential for vital cellular processes, including DNA synthesis, repair, and proliferation, necessitating enhanced iron uptake and intracellular accumulation. Tumor cells, in particular, exhibit a pronounced elevation in iron uptake to sustain their continuous proliferation, migration and in...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Bin Li, Bing Zhang, Ziyue Cheng, Yantao Lou, Shuqiu Chen
Formatua:	Artikulua
Hizkuntza:	English
Argitaratua:	Frontiers Media S.A. 2025-03-01
Saila:	Frontiers in Bioengineering and Biotechnology
Gaiak:	iron metabolism transferrin receptors cancer therapy iron chelators nanocarriers
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fbioe.2025.1511197/full

Antzeko izenburuak

Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction
nork: Dong Guo, et al.
Argitaratua: (2024-08-01)

Dysregulated Iron Homeostasis as Common Disease Etiology and Promising Therapeutic Target
nork: Bruce E. Holbein, et al.
Argitaratua: (2023-03-01)

Iron-chelating and anti-lipid peroxidation properties of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in long-term iron loading β-thalassemic mice
nork: Kanokwan Kulprachakarn, et al.
Argitaratua: (2014-08-01)

Iron metabolism
nork: Ana Maria de Souza
Argitaratua: (2005-06-01)

Klebsiella pneumoniae manipulates human macrophages to acquire iron
nork: Philipp Grubwieser, et al.
Argitaratua: (2023-08-01)

CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis
nork: Mohammad Golam Sabbir
Argitaratua: (2020-05-01)

Host and microbiota derived extracellular vesicles: Crucial players in iron homeostasis
nork: Yasmeen Daou, et al.
Argitaratua: (2022-10-01)

Specific parameters of iron metabolism in tuberculosis
nork: R. Yu. Аbdullаev, et al.
Argitaratua: (2021-04-01)

The Fate of Iron in The Organism and Its Regulatory Pathways
nork: Přemysl Mladěnka, et al.
Argitaratua: (2005-01-01)

Iron and Acinetobacter baumannii Biofilm Formation
nork: Valentina Gentile, et al.
Argitaratua: (2014-08-01)

A Mini-Review on Iron Chelating Agents as a Promising Therapeutic Target in Treatment of Leishmaniasis
nork: Mahdi Fakhar, et al.
Argitaratua: (2020-05-01)

The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body.
nork: Christal A Worthen, et al.
Argitaratua: (2014-03-01)

Iron, hepcidin and the metal connection.
nork: Olivier eLoréal, et al.
Argitaratua: (2014-06-01)

Effect of Deferoxamine on Post-Transfusion Iron, Inflammation, and In Vitro Microbial Growth in a Canine Hemorrhagic Shock Model: A Randomized Controlled Blinded Pilot Study
nork: Melissa A. Claus, et al.
Argitaratua: (2023-02-01)

From Rust to Quantum Biology: The Role of Iron in Retina Physiopathology
nork: Emilie Picard, et al.
Argitaratua: (2020-03-01)

Abnormal Serum Iron-Status Indicator Changes in Amyotrophic Lateral Sclerosis (ALS) Patients: A Meta-Analysis
nork: Lan Wang, et al.
Argitaratua: (2020-05-01)

Role of Flavonoids in the Treatment of Iron Overload
nork: Xiaomin Wang, et al.
Argitaratua: (2021-07-01)

Influence of serum transferrin concentration on diagnostic criteria for iron deficiency in chronic heart failure
nork: Fraser J. Graham, et al.
Argitaratua: (2023-10-01)

Transferrin receptor 2 is emerging as a major player in the control of iron metabolism
nork: Calzolari Alessia, et al.
Argitaratua: (2007-03-01)

The usefulness of soluble transferrin receptor in the diagnosis and treatment of iron deficiency anemia in children
nork: Se Hoon Yoon, et al.
Argitaratua: (2015-01-01)

Iron homeostasis imbalance and ferroptosis in brain diseases
nork: Haining Long, et al.
Argitaratua: (2023-08-01)

Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases
nork: George J. Kontoghiorghes, et al.
Argitaratua: (2020-06-01)

Challenges and strategies to combat global iron deficiency by food fortification
nork: R. M. P. I. Rajakaruna, et al.
Argitaratua: (2016-09-01)

Study of Soluble Transferrin Receptor/Log Ferritin Ratio as a Determinant of Body Iron in Young Healthy Non Pregnant Females
nork: Eram Hussain Pasha, et al.
Argitaratua: (2018-03-01)

Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrin
nork: Shannon L. Rhodes, et al.
Argitaratua: (2014-02-01)

Association Between Iron Status and Risk of Chronic Kidney Disease in Chinese Adults
nork: Yongjian Zhu, et al.
Argitaratua: (2020-01-01)

Iron Metabolism in Prostate Cancer; From Basic Science to New Therapeutic Strategies
nork: Driton Vela
Argitaratua: (2018-11-01)

Pathophysiological aspects of transferrin-A potential nano-based drug delivery signaling molecule in therapeutic target for varied diseases
nork: Chang Li, et al.
Argitaratua: (2024-03-01)

Anaemia control and the interpretation of biochemical tests for iron status in children
nork: Thando P. Gwetu, et al.
Argitaratua: (2017-04-01)

Effects of Exogenous Transferrin on the Regulation of Iron Metabolism and Erythropoiesis in Iron Deficiency With or Without Anemia
nork: Yihang Li, et al.
Argitaratua: (2022-05-01)

The significance of soluble transferrin receptors in diagnosing iron deficiency anemia
nork: Tijanić Ivan, et al.
Argitaratua: (2015-08-01)

The modified method for blood serum labile iron quantification
nork: I. Chumachenko, et al.
Argitaratua: (2016-11-01)

Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs
nork: Masanori Yoshinaga, et al.
Argitaratua: (2017-05-01)

Local iron deficiency in the substantia nigra directly contributes to hyperlocomotion phenotypes
nork: Zhuo Wang, et al.
Argitaratua: (2022-06-01)

Serum ferritin to detect iron deficiency in children below five years of age
nork: Windy Saufia Apriyanti, et al.
Argitaratua: (2013-06-01)

Naringin is a promising natural compound for therapy of iron-overload disorders
nork: Mehrdad Jahanshahi, et al.
Argitaratua: (2022-07-01)

Dysregulation of iron metabolism modulators in virologically suppressed HIV-infected patients
nork: Vanesa Garrido-Rodríguez, et al.
Argitaratua: (2022-11-01)

New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases
nork: Marco T. Nuñez, et al.
Argitaratua: (2018-10-01)

Effect of iron status on myocardial infarction: A two-sample Mendelian randomization study
nork: Xiaozhuo Xu, et al.
Argitaratua: (2024-12-01)

Blood labile iron effect on nitrosative stress development under rat experimental rhabdomyolysis
nork: I. M. Chumachenko, et al.
Argitaratua: (2012-12-01)