Characterization of Inhibitory Effectiveness in Hyperpolarization-Activated Cation Currents by a Group of <i>ent</i>-Kaurane-Type Diterpenoids from <i>Croton tonkinensis</i>

Characterization of Inhibitory Effectiveness in Hyperpolarization-Activated Cation Currents by a Group of <i>ent</i>-Kaurane-Type Diterpenoids from <i>Croton tonkinensis</i>

Croton is an extensive flowering plant genus in the spurge family, Euphorbiaceae. Three croton compounds with the common <i>ent</i>-kaurane skeleton have been purified from <i>Croton tonkinensis</i>. Methods: We examined any modifications of croton components (i.e., croton-01...

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Bibliographic Details
Main Authors: Ping-Chung Kuo, Yen-Chin Liu, Yi-Ching Lo, Sheng-Nan Wu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
croton
pituitary cell
pancreatic β-cell
hyperpolarization-activated cation current
<i>erg</i>-mediated k<sup>+</sup> current
membrane potential
Online Access:https://www.mdpi.com/1422-0067/21/4/1268

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