Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism

ABSTRACT Objective To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of te...

Full description

Bibliographic Details
Main Authors: Rita V. Weiss, Alexandre Hohl, Amanda Athayde, Dolores Pardini, Larissa Gomes, Monica de Oliveira, Ricardo Meirelles, Ruth Clapauch, Poli Mara Spritzer
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism
Series:Archives of Endocrinology and Metabolism
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000600190&lng=en&tlng=en
_version_ 1818481586766610432
author Rita V. Weiss
Alexandre Hohl
Amanda Athayde
Dolores Pardini
Larissa Gomes
Monica de Oliveira
Ricardo Meirelles
Ruth Clapauch
Poli Mara Spritzer
author_facet Rita V. Weiss
Alexandre Hohl
Amanda Athayde
Dolores Pardini
Larissa Gomes
Monica de Oliveira
Ricardo Meirelles
Ruth Clapauch
Poli Mara Spritzer
author_sort Rita V. Weiss
collection DOAJ
description ABSTRACT Objective To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription. Arch Endocrinol Metab. 2019;63(3):190-8
first_indexed 2024-12-10T11:36:56Z
format Article
id doaj.art-cb7589fe305d47e9888cf2643a72010c
institution Directory Open Access Journal
issn 2359-4292
language English
last_indexed 2024-12-10T11:36:56Z
publisher Brazilian Society of Endocrinology and Metabolism
record_format Article
series Archives of Endocrinology and Metabolism
spelling doaj.art-cb7589fe305d47e9888cf2643a72010c2022-12-22T01:50:24ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-429263319019810.20945/2359-3997000000152S2359-39972019000600190Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and MetabolismRita V. WeissAlexandre HohlAmanda AthaydeDolores PardiniLarissa GomesMonica de OliveiraRicardo MeirellesRuth ClapauchPoli Mara SpritzerABSTRACT Objective To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription. Arch Endocrinol Metab. 2019;63(3):190-8http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000600190&lng=en&tlng=enTestosterone therapyfemale sexual disorderposition
spellingShingle Rita V. Weiss
Alexandre Hohl
Amanda Athayde
Dolores Pardini
Larissa Gomes
Monica de Oliveira
Ricardo Meirelles
Ruth Clapauch
Poli Mara Spritzer
Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
Archives of Endocrinology and Metabolism
Testosterone therapy
female sexual disorder
position
title Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
title_full Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
title_fullStr Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
title_full_unstemmed Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
title_short Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
title_sort testosterone therapy for women with low sexual desire a position statement from the brazilian society of endocrinology and metabolism
topic Testosterone therapy
female sexual disorder
position
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000600190&lng=en&tlng=en
work_keys_str_mv AT ritavweiss testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT alexandrehohl testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT amandaathayde testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT dolorespardini testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT larissagomes testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT monicadeoliveira testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT ricardomeirelles testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT ruthclapauch testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism
AT polimaraspritzer testosteronetherapyforwomenwithlowsexualdesireapositionstatementfromthebraziliansocietyofendocrinologyandmetabolism