Longitudinal Intraindividual Cognitive Variability Is Associated With Reduction in Regional Cerebral Blood Flow Among Alzheimer’s Disease Biomarker-Positive Older Adults

Longitudinal Intraindividual Cognitive Variability Is Associated With Reduction in Regional Cerebral Blood Flow Among Alzheimer’s Disease Biomarker-Positive Older Adults

Intraindividual variability (IIV) across neuropsychological measures within a single testing session is a promising marker predictive of cognitive decline and development of Alzheimer’s disease (AD). We have previously shown that greater IIV is cross-sectionally associated with reduced cerebral bloo...

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Bibliographic Details
Main Authors: Sophia L. Holmqvist, Kelsey R. Thomas, Einat K. Brenner, Emily C. Edmonds, Amanda Calcetas, Lauren Edwards, Maria Bordyug, Katherine J. Bangen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
neuropsychology
intra-individual variability
aging
cerebral blood flow (CBF)
magnetic resonance imaging (MRI)
Alzheimer’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.859873/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.859873/full

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