Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility. In this study, we enhanced the solubility, bioavailability, and stability of TEL through the fabrication of TEL-loaded pH-modulated solid dispe...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Bhupendra Raj Giri, Jaewook Kwon, Anh Q. Vo, Ajinkya M. Bhagurkar, Suresh Bandari, Dong Wuk Kim
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2021-01-01
Cyfres:Pharmaceuticals
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/1424-8247/14/1/73