Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility. In this study, we enhanced the solubility, bioavailability, and stability of TEL through the fabrication of TEL-loaded pH-modulated solid dispe...

詳細記述

書誌詳細
主要な著者: Bhupendra Raj Giri, Jaewook Kwon, Anh Q. Vo, Ajinkya M. Bhagurkar, Suresh Bandari, Dong Wuk Kim
フォーマット: 論文
言語:English
出版事項: MDPI AG 2021-01-01
シリーズ:Pharmaceuticals
主題:
オンライン・アクセス:https://www.mdpi.com/1424-8247/14/1/73