Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm
Background: Picking up of the clinical significance of pulmonary opacities in patients with extra- pulmonary malignancy is an urgent need for evaluating it. As, most physicians expect them to be pulmonary metastases which are deemed incurable and are assigned to palliative treatment. This assumption...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-10-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0422763817301516 |
| _version_ | 1811278748479127552 |
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| author | Ahmed Mohamed Said Samah M. Shehata Samah Mohamed Lutfy Ahmed Elsammak Ahmed El-Azony Mona Roshdy |
| author_facet | Ahmed Mohamed Said Samah M. Shehata Samah Mohamed Lutfy Ahmed Elsammak Ahmed El-Azony Mona Roshdy |
| author_sort | Ahmed Mohamed Said |
| collection | DOAJ |
| description | Background: Picking up of the clinical significance of pulmonary opacities in patients with extra- pulmonary malignancy is an urgent need for evaluating it. As, most physicians expect them to be pulmonary metastases which are deemed incurable and are assigned to palliative treatment. This assumption directly affects the treatment and prognosis of patients.
Aim of the study: Is to investigate the clinical significance of pulmonary shadows in these patients, and to distinguish malignant from benign opacities and attention should be paid to the pathological diagnosis of those opacities in order to avoid over or under treatment.
Patients and Methods: Prospective, observational study conducted in Chest and Oncology departments, Zagazig University Hospitals, in the period from October 2014 to September 2016. The study was carried out on 100 patients with pathologically and clinically proved extrapulmonary malignant neoplasm and different radiological pulmonary lesions undiagnosed. CT chest and bronchoscopy were done for all patients and Samples were subjected to cytology, histopathology, AFB staining, fungal smear and culture/sensitivity, depending upon the findings.
Results: The results of pathological types of lung lesions revealed that metastatic lesions (69%) were the commonest followed by benign lesions (18%) and primary lung cancer (13%). Patients with current smoking history and advanced stage of primary tumor have significant liability to have lung malignancy. Also, patients who showed multiple pulmonary nodules, ground glass opacities and mass in their CT finding have higher liability to have lung malignancy rather than other findings with high statistical significance (P value <0.001).
Conclusion: Patients presented with advanced stages of primary extrapulmonary malignancy, current or former smokers, with multiple pulmonary nodules or mass in computed tomography of the chest, were more liable for being malignant and needs diagnostic biopsies. |
| first_indexed | 2024-04-13T00:41:34Z |
| format | Article |
| id | doaj.art-cb7bf82090e84de08b3479d1b1c9511a |
| institution | Directory Open Access Journal |
| issn | 0422-7638 |
| language | English |
| last_indexed | 2024-04-13T00:41:34Z |
| publishDate | 2017-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj.art-cb7bf82090e84de08b3479d1b1c9511a2022-12-22T03:10:08ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382017-10-0166468168610.1016/j.ejcdt.2017.09.001Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasmAhmed Mohamed Said0Samah M. Shehata1Samah Mohamed Lutfy2Ahmed Elsammak3Ahmed El-Azony4Mona Roshdy5Chest Department, Zagazig University, EgyptChest Department, Zagazig University, EgyptChest Department, Zagazig University, EgyptRadiodiagnosis Department, Zagazig University, EgyptClinical Oncology Department, Zagazig University, EgyptPathology Department, Zagazig University, EgyptBackground: Picking up of the clinical significance of pulmonary opacities in patients with extra- pulmonary malignancy is an urgent need for evaluating it. As, most physicians expect them to be pulmonary metastases which are deemed incurable and are assigned to palliative treatment. This assumption directly affects the treatment and prognosis of patients. Aim of the study: Is to investigate the clinical significance of pulmonary shadows in these patients, and to distinguish malignant from benign opacities and attention should be paid to the pathological diagnosis of those opacities in order to avoid over or under treatment. Patients and Methods: Prospective, observational study conducted in Chest and Oncology departments, Zagazig University Hospitals, in the period from October 2014 to September 2016. The study was carried out on 100 patients with pathologically and clinically proved extrapulmonary malignant neoplasm and different radiological pulmonary lesions undiagnosed. CT chest and bronchoscopy were done for all patients and Samples were subjected to cytology, histopathology, AFB staining, fungal smear and culture/sensitivity, depending upon the findings. Results: The results of pathological types of lung lesions revealed that metastatic lesions (69%) were the commonest followed by benign lesions (18%) and primary lung cancer (13%). Patients with current smoking history and advanced stage of primary tumor have significant liability to have lung malignancy. Also, patients who showed multiple pulmonary nodules, ground glass opacities and mass in their CT finding have higher liability to have lung malignancy rather than other findings with high statistical significance (P value <0.001). Conclusion: Patients presented with advanced stages of primary extrapulmonary malignancy, current or former smokers, with multiple pulmonary nodules or mass in computed tomography of the chest, were more liable for being malignant and needs diagnostic biopsies.http://www.sciencedirect.com/science/article/pii/S0422763817301516Pulmonary shadowsExtra pulmonary neoplasmFibroptic bronchoscopy |
| spellingShingle | Ahmed Mohamed Said Samah M. Shehata Samah Mohamed Lutfy Ahmed Elsammak Ahmed El-Azony Mona Roshdy Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm Egyptian Journal of Chest Disease and Tuberculosis Pulmonary shadows Extra pulmonary neoplasm Fibroptic bronchoscopy |
| title | Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| title_full | Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| title_fullStr | Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| title_full_unstemmed | Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| title_short | Assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| title_sort | assessment of radiological pulmonary shadows in patients with extra pulmonary neoplasm |
| topic | Pulmonary shadows Extra pulmonary neoplasm Fibroptic bronchoscopy |
| url | http://www.sciencedirect.com/science/article/pii/S0422763817301516 |
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