A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus
The mechanism of tinnitus suppression after cochlear implantation (CI) in single-sided deafness (SSD) is not fully understood. In this regard, by comparing pre- and post-CI quantitative electroencephalography (qEEG), we explored cortical changes relevant to tinnitus improvement. In SSD patients who...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-05-01
|
Series: | Frontiers in Human Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00210/full |
_version_ | 1811268196522524672 |
---|---|
author | Jae-Jin Song Kyungsoo Kim Woongsang Sunwoo Griet Mertens Paul Van de Heyning Dirk De Ridder Sven Vanneste Sang-Youp Lee Kyung-Joon Park Hongsoo Choi Ji-Woong Choi |
author_facet | Jae-Jin Song Kyungsoo Kim Woongsang Sunwoo Griet Mertens Paul Van de Heyning Dirk De Ridder Sven Vanneste Sang-Youp Lee Kyung-Joon Park Hongsoo Choi Ji-Woong Choi |
author_sort | Jae-Jin Song |
collection | DOAJ |
description | The mechanism of tinnitus suppression after cochlear implantation (CI) in single-sided deafness (SSD) is not fully understood. In this regard, by comparing pre- and post-CI quantitative electroencephalography (qEEG), we explored cortical changes relevant to tinnitus improvement. In SSD patients who underwent CI, qEEG data were collected: (1) before CI, (2) 6 months post-operatively with CI-on, and (3) 30 min after CI-off and source-localized cortical activity/functional connectivity analyses were performed. Compared to the pre-operative baseline, the CI-on condition demonstrated significantly decreased activity in the right auditory- and orbitofrontal cortices (OFC) for the delta frequency band as well as decreased connectivity between the auditory cortex/posterior cingulate cortex for the delta/beta2 bands. Meanwhile, compared to the CI-off condition, the CI-on condition displayed decreased activity in the right auditory cortices/OFC for the delta band, and in bilateral auditory cortices, left inferior frontal cortex/OFC for the gamma band. However, qEEG analyses showed no significant differences between the CI-off and baseline conditions. CI induced overall decreased cortical activity and functional connectivity. However, judging from no differences between the CI-off and baseline conditions, CI-induced cortical activity and functional connectivity changes are not by cortical plastic changes, but by dynamic peripheral reafferentation. |
first_indexed | 2024-04-12T21:17:26Z |
format | Article |
id | doaj.art-cb7f2cf31dbc46d9bd59af1bd0126344 |
institution | Directory Open Access Journal |
issn | 1662-5161 |
language | English |
last_indexed | 2024-04-12T21:17:26Z |
publishDate | 2017-05-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Human Neuroscience |
spelling | doaj.art-cb7f2cf31dbc46d9bd59af1bd01263442022-12-22T03:16:24ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612017-05-011110.3389/fnhum.2017.00210242300A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with TinnitusJae-Jin Song0Kyungsoo Kim1Woongsang Sunwoo2Griet Mertens3Paul Van de Heyning4Dirk De Ridder5Sven Vanneste6Sang-Youp Lee7Kyung-Joon Park8Hongsoo Choi9Ji-Woong Choi10Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Information and Communication Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu, South KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Otorhinolaryngology and Head and Neck Surgery, University Hospital Antwerp, Edegem, BelgiumDepartment of Otorhinolaryngology and Head and Neck Surgery, University Hospital Antwerp, Edegem, BelgiumDepartment of Surgical Sciences, Section of Neurosurgery, Dunedin School of Medicine, University of Otago, Dunedin, New ZealandLab for Clinical and Integrative Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USADepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Information and Communication Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu, South KoreaDepartment of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu, South KoreaDepartment of Information and Communication Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu, South KoreaThe mechanism of tinnitus suppression after cochlear implantation (CI) in single-sided deafness (SSD) is not fully understood. In this regard, by comparing pre- and post-CI quantitative electroencephalography (qEEG), we explored cortical changes relevant to tinnitus improvement. In SSD patients who underwent CI, qEEG data were collected: (1) before CI, (2) 6 months post-operatively with CI-on, and (3) 30 min after CI-off and source-localized cortical activity/functional connectivity analyses were performed. Compared to the pre-operative baseline, the CI-on condition demonstrated significantly decreased activity in the right auditory- and orbitofrontal cortices (OFC) for the delta frequency band as well as decreased connectivity between the auditory cortex/posterior cingulate cortex for the delta/beta2 bands. Meanwhile, compared to the CI-off condition, the CI-on condition displayed decreased activity in the right auditory cortices/OFC for the delta band, and in bilateral auditory cortices, left inferior frontal cortex/OFC for the gamma band. However, qEEG analyses showed no significant differences between the CI-off and baseline conditions. CI induced overall decreased cortical activity and functional connectivity. However, judging from no differences between the CI-off and baseline conditions, CI-induced cortical activity and functional connectivity changes are not by cortical plastic changes, but by dynamic peripheral reafferentation.http://journal.frontiersin.org/article/10.3389/fnhum.2017.00210/fullsingle side deafnesstinnituscochlear implantationelectroencephalographydynamic peripheral reafferentation |
spellingShingle | Jae-Jin Song Kyungsoo Kim Woongsang Sunwoo Griet Mertens Paul Van de Heyning Dirk De Ridder Sven Vanneste Sang-Youp Lee Kyung-Joon Park Hongsoo Choi Ji-Woong Choi A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus Frontiers in Human Neuroscience single side deafness tinnitus cochlear implantation electroencephalography dynamic peripheral reafferentation |
title | A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus |
title_full | A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus |
title_fullStr | A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus |
title_full_unstemmed | A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus |
title_short | A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus |
title_sort | quantitative electroencephalography study on cochlear implant induced cortical changes in single sided deafness with tinnitus |
topic | single side deafness tinnitus cochlear implantation electroencephalography dynamic peripheral reafferentation |
url | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00210/full |
work_keys_str_mv | AT jaejinsong aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT kyungsookim aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT woongsangsunwoo aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT grietmertens aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT paulvandeheyning aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT dirkderidder aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT svenvanneste aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT sangyouplee aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT kyungjoonpark aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT hongsoochoi aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT jiwoongchoi aquantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT jaejinsong quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT kyungsookim quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT woongsangsunwoo quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT grietmertens quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT paulvandeheyning quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT dirkderidder quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT svenvanneste quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT sangyouplee quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT kyungjoonpark quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT hongsoochoi quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus AT jiwoongchoi quantitativeelectroencephalographystudyoncochlearimplantinducedcorticalchangesinsinglesideddeafnesswithtinnitus |