Harlequin Ichthyosis: Case Report

Harlequin Ichthyosis: Case Report

Harlequin ichthyosis is a rare autosomal recessive congenital disease in which neonates present generalized hyperkeratotic plaques and deep fissures, ectropion, eclabium, malformation of the auricular pavilion and typical facies. Although several complications related to the skin restriction may occ...

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Bibliographic Details
Main Authors: Patrícia A. Couto, Marcela C. Pastore, Jessica C. N. Araújo, Cecilya M. Mota, Caroline A. R. Chirano, Valeria K. A. Ferreira, Sidharta Q. Gadelha, Elaine D. Melo, Patricia C. B. de Melo, Luciana M. Santos
Format: Article
Language:English
Published: Sociedade Portuguesa de Dermatologia e Venereologia 2019-03-01
Series:Revista da Sociedade Portuguesa de Dermatologia e Venereologia
Subjects:
ATP-Binding Cassette Transporters
Ichthyosis
Lamellar
Infant
Newborn
Online Access:https://revista.spdv.com.pt/index.php/spdv/article/view/984
Description
Summary:Harlequin ichthyosis is a rare autosomal recessive congenital disease in which neonates present generalized hyperkeratotic plaques and deep fissures, ectropion, eclabium, malformation of the auricular pavilion and typical facies. Although several complications related to the skin restriction may occur, support in intensive care and early introduction of systemic retinoids, such as acitretin, have significantly contributed to patients' survival and improved prognosis. The purpose of this report is to present a rare case of harlequin ichthyosis and to discuss strategies for early diagnosis and first supportive care.
ISSN:2182-2395
2182-2409

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