Stress-protective action of herbal adaptogens in experiment

In recent years the main mortality reasons were coronary heart disease, hypertension, cancer, peptic and duodenal ulcers, mental illness. Provoking factor of these diseases is chronic stress. It activates lipid peroxidation, which is one of the damaging factors for the internal organs. In the presen...

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Main Authors: S. T. Kokhan, A. V. Pateyuk, E. M. Krivosheyeva
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2015-05-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/68
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author S. T. Kokhan
A. V. Pateyuk
E. M. Krivosheyeva
author_facet S. T. Kokhan
A. V. Pateyuk
E. M. Krivosheyeva
author_sort S. T. Kokhan
collection DOAJ
description In recent years the main mortality reasons were coronary heart disease, hypertension, cancer, peptic and duodenal ulcers, mental illness. Provoking factor of these diseases is chronic stress. It activates lipid peroxidation, which is one of the damaging factors for the internal organs. In the present study, we investigated the possibility to increase stress resistance and to find pathogenetic grounding of the use of plant adaptogens - astragalus, ginseng, and "Arur Tan N 7" in experimental stress. We have shown that all herbal remedies improve metabolic processes in the tissues of experimental animals and regulate the processes of free radical oxidation. Studies have shown that phyto remedy "Arur-Tan N 7 "shows antiradical activity against NO-binding radicals comparable to that of quercetin, rutin and hydroquinone. On this basis, phyto remedy "Arur-Tan N 7" was more effective in animals in simulation of stress induced by strenuous activity, it restores cells energy potential, normalizes "lipid peroxidation - antioxidant protection" balance and maintains the balance of thiols in animal body. Moreover, all tested herbal remedies at the dosages used are not toxic and therefore can be recommended for further studies.
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spelling doaj.art-cb856f43ba344bd5b90304d8964f398f2024-03-28T07:49:14ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962015-05-0103384268Stress-protective action of herbal adaptogens in experimentS. T. Kokhan0A. V. Pateyuk1E. M. Krivosheyeva2Transbaikal State UniversityTransbaikal State UniversityTransbaikal State UniversityIn recent years the main mortality reasons were coronary heart disease, hypertension, cancer, peptic and duodenal ulcers, mental illness. Provoking factor of these diseases is chronic stress. It activates lipid peroxidation, which is one of the damaging factors for the internal organs. In the present study, we investigated the possibility to increase stress resistance and to find pathogenetic grounding of the use of plant adaptogens - astragalus, ginseng, and "Arur Tan N 7" in experimental stress. We have shown that all herbal remedies improve metabolic processes in the tissues of experimental animals and regulate the processes of free radical oxidation. Studies have shown that phyto remedy "Arur-Tan N 7 "shows antiradical activity against NO-binding radicals comparable to that of quercetin, rutin and hydroquinone. On this basis, phyto remedy "Arur-Tan N 7" was more effective in animals in simulation of stress induced by strenuous activity, it restores cells energy potential, normalizes "lipid peroxidation - antioxidant protection" balance and maintains the balance of thiols in animal body. Moreover, all tested herbal remedies at the dosages used are not toxic and therefore can be recommended for further studies.https://www.actabiomedica.ru/jour/article/view/68«арура-тан №7»stressherbal adaptogensastragal“arura-tan n 7”lipid peroxidation
spellingShingle S. T. Kokhan
A. V. Pateyuk
E. M. Krivosheyeva
Stress-protective action of herbal adaptogens in experiment
Acta Biomedica Scientifica
«арура-тан №7»
stress
herbal adaptogens
astragal
“arura-tan n 7”
lipid peroxidation
title Stress-protective action of herbal adaptogens in experiment
title_full Stress-protective action of herbal adaptogens in experiment
title_fullStr Stress-protective action of herbal adaptogens in experiment
title_full_unstemmed Stress-protective action of herbal adaptogens in experiment
title_short Stress-protective action of herbal adaptogens in experiment
title_sort stress protective action of herbal adaptogens in experiment
topic «арура-тан №7»
stress
herbal adaptogens
astragal
“arura-tan n 7”
lipid peroxidation
url https://www.actabiomedica.ru/jour/article/view/68
work_keys_str_mv AT stkokhan stressprotectiveactionofherbaladaptogensinexperiment
AT avpateyuk stressprotectiveactionofherbaladaptogensinexperiment
AT emkrivosheyeva stressprotectiveactionofherbaladaptogensinexperiment