Looking beyond the magic bullet: Novel asthma drugs or education which works better
Although Ë‚5% of children with asthma suffer from severe asthma, they account for the highest use of health resources. The field of asthma therapy is changing rapidly, with a number of new drugs and biologics being added to the treatment armamentarium, particularly for adults. This, though, is not t...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
South African Medical Association
2018-07-01
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| Series: | South African Medical Journal |
| Online Access: | http://www.samj.org.za/index.php/samj/article/download/12365/8557 |
| _version_ | 1797368194220949504 |
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| author | R Masekela M Levin P Jeena M Annamalai V Naidoo A van Niekerk D Hawarden S Emanuel H Katz H Zar R Green F Kritzinger A Manjra; on behalf of the South African Childhood Asthma Working Group (SACAWG) |
| author_facet | R Masekela M Levin P Jeena M Annamalai V Naidoo A van Niekerk D Hawarden S Emanuel H Katz H Zar R Green F Kritzinger A Manjra; on behalf of the South African Childhood Asthma Working Group (SACAWG) |
| author_sort | R Masekela |
| collection | DOAJ |
| description | Although Ë‚5% of children with asthma suffer from severe asthma, they account for the highest use of health resources. The field of asthma therapy is changing rapidly, with a number of new drugs and biologics being added to the treatment armamentarium, particularly for adults. This, though, is not the case for paediatric patients, in whom a number of these novel molecules and drugs have not been investigated. Even though adults have shown responses to medication in some studies, this does not necessarily imply that there will be similar results in children. In the management of severe asthma, use of specific interventions to ensure treatment adherence and goal-setting for self-management is critical to ensure the best treatment outcomes. The objective of this article is to review and grade the current evidence base for use of novel asthma drugs and to make evidence-based recommendations for their administration in children with severe asthma in the South Africa context. We also review the evidence for medication-adherence strategies and self-management plans. |
| first_indexed | 2024-03-08T17:28:03Z |
| format | Article |
| id | doaj.art-cb857ad10192468a86522dc9381a51e8 |
| institution | Directory Open Access Journal |
| issn | 0256-9574 2078-5135 |
| language | English |
| last_indexed | 2024-03-08T17:28:03Z |
| publishDate | 2018-07-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj.art-cb857ad10192468a86522dc9381a51e82024-01-02T17:36:53ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352018-07-01108861962310.7196/SAMJ.2018.v108i8.13163Looking beyond the magic bullet: Novel asthma drugs or education which works betterR MasekelaM LevinP JeenaM AnnamalaiV NaidooA van NiekerkD HawardenS EmanuelH KatzH ZarR GreenF KritzingerA Manjra; on behalf of the South African Childhood Asthma Working Group (SACAWG)Although Ë‚5% of children with asthma suffer from severe asthma, they account for the highest use of health resources. The field of asthma therapy is changing rapidly, with a number of new drugs and biologics being added to the treatment armamentarium, particularly for adults. This, though, is not the case for paediatric patients, in whom a number of these novel molecules and drugs have not been investigated. Even though adults have shown responses to medication in some studies, this does not necessarily imply that there will be similar results in children. In the management of severe asthma, use of specific interventions to ensure treatment adherence and goal-setting for self-management is critical to ensure the best treatment outcomes. The objective of this article is to review and grade the current evidence base for use of novel asthma drugs and to make evidence-based recommendations for their administration in children with severe asthma in the South Africa context. We also review the evidence for medication-adherence strategies and self-management plans.http://www.samj.org.za/index.php/samj/article/download/12365/8557 |
| spellingShingle | R Masekela M Levin P Jeena M Annamalai V Naidoo A van Niekerk D Hawarden S Emanuel H Katz H Zar R Green F Kritzinger A Manjra; on behalf of the South African Childhood Asthma Working Group (SACAWG) Looking beyond the magic bullet: Novel asthma drugs or education which works better South African Medical Journal |
| title | Looking beyond the magic bullet: Novel asthma drugs or education which works better |
| title_full | Looking beyond the magic bullet: Novel asthma drugs or education which works better |
| title_fullStr | Looking beyond the magic bullet: Novel asthma drugs or education which works better |
| title_full_unstemmed | Looking beyond the magic bullet: Novel asthma drugs or education which works better |
| title_short | Looking beyond the magic bullet: Novel asthma drugs or education which works better |
| title_sort | looking beyond the magic bullet novel asthma drugs or education which works better |
| url | http://www.samj.org.za/index.php/samj/article/download/12365/8557 |
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