Modeling the Interplay between HDV and HBV in Chronic HDV/HBV Patients

Modeling the Interplay between HDV and HBV in Chronic HDV/HBV Patients

Hepatitis D virus is an infectious subviral agent that can only propagate in people infected with hepatitis B virus. In this study, we modified and further developed a recent model for early hepatitis D virus and hepatitis B virus kinetics to better reproduce hepatitis D virus and hepatitis B virus...

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Bibliographic Details
Main Authors: Adequate Mhlanga, Rami Zakh, Alexander Churkin, Vladimir Reinharz, Jeffrey S. Glenn, Ohad Etzion, Scott J. Cotler, Cihan Yurdaydin, Danny Barash, Harel Dahari
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Mathematics
Subjects:
hepatitis delta virus
hepatitis B virus
anti-HDV treatment
analytical solution
Online Access:https://www.mdpi.com/2227-7390/10/20/3917
Description
Summary:Hepatitis D virus is an infectious subviral agent that can only propagate in people infected with hepatitis B virus. In this study, we modified and further developed a recent model for early hepatitis D virus and hepatitis B virus kinetics to better reproduce hepatitis D virus and hepatitis B virus kinetics measured in infected patients during anti-hepatitis D virus treatment. The analytical solutions were provided to highlight the new features of the modified model. The improved model offered significantly better prospects for modeling hepatitis D virus and hepatitis B virus interactions.
ISSN:2227-7390

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