Early Changes in Apparent Diffusion Coefficient Predict the Quantitative Antitumoral Activity of Capecitabine, Oxaliplatin, and Irradiation in HT29 Xenografts in Athymic Nude Mice

Early Changes in Apparent Diffusion Coefficient Predict the Quantitative Antitumoral Activity of Capecitabine, Oxaliplatin, and Irradiation in HT29 Xenografts in Athymic Nude Mice

PURPOSE: The purpose of this study was to evaluate the possible use of changes in apparent diffusion coefficient (ADC) measured by magnetic resonance imaging for pretreatment prediction and early detection of tumor response in a mouse model during fractionated chemoradiotherapy. MATERIALS AND METHOD...

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Bibliographic Details
Main Authors: Therese Seierstad, Sigurd Folkvord, Kathrine Røe, Kjersti Flatmark, Arne Skretting, Dag Rune Olsen
Format: Article
Language:English
Published: Elsevier 2007-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Apparent diffusion coefficient
HT29
oxaliplatin
capecitabine
prediction of therapy response
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800893

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