RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes

RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes

Adaptive biological mechanisms to hypoxia are crucial to maintain oxygen homeostasis, especially in the brain. Pericytes, cells uniquely positioned at the blood-brain interface, respond fast to hypoxia by expressing regulator of G-protein signalling 5 (RGS5), a negative regulator of G-protein-couple...

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Bibliographic Details
Main Authors: Andreas Enström, Robert Carlsson, Ilknur Özen, Gesine Paul
Format: Article
Language:English
Published: The Company of Biologists 2022-10-01
Series:Biology Open
Subjects:
hypoxia
migration
pdgfbb
pericytes
rgs5
s1p
Online Access:http://bio.biologists.org/content/11/10/bio059371

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