Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up
Objective: To determine the 5-year post-transplant survival ofpatients with multiple myeloma. Methods: A retrospective study inpatients diagnosed with multiple myeloma submitted to autologousbone marrow transplantation at a Brazilian institution, during theperiod of 1993 to 2007. Results: Seventy-th...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto Israelita de Ensino e Pesquisa Albert Einstein
2011-06-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://apps.einstein.br/revista/arquivos/PDF/1845-Einstein_v9n2_119-123.pdf |
| Summary: | Objective: To determine the 5-year post-transplant survival ofpatients with multiple myeloma. Methods: A retrospective study inpatients diagnosed with multiple myeloma submitted to autologousbone marrow transplantation at a Brazilian institution, during theperiod of 1993 to 2007. Results: Seventy-three patients wereevaluated with a median age of 55 years. Survival in 5 years was75% (2.4 to 60 months). Statistical analysis demonstrated statisticalsignificance for the applied grade of response prior to treatment withautologous bone marrow transplantation (p = 0.01). There was nostatistical significance for clinical staging or time of diagnosis (before or after the year 2000). Conclusion: Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients. |
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| ISSN: | 1679-4508 |