Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represe...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1260478/full |
| _version_ | 1797654453742993408 |
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| author | Aleksandra Djokovic Aleksandra Djokovic Gordana Krljanac Gordana Krljanac Predrag Matic Predrag Matic Rastko Zivic Rastko Zivic Vuk Djulejic Vuk Djulejic Marija Marjanovic Haljilji Dusan Popovic Dusan Popovic Branka Filipovic Branka Filipovic Svetlana Apostolovic Svetlana Apostolovic |
| author_facet | Aleksandra Djokovic Aleksandra Djokovic Gordana Krljanac Gordana Krljanac Predrag Matic Predrag Matic Rastko Zivic Rastko Zivic Vuk Djulejic Vuk Djulejic Marija Marjanovic Haljilji Dusan Popovic Dusan Popovic Branka Filipovic Branka Filipovic Svetlana Apostolovic Svetlana Apostolovic |
| author_sort | Aleksandra Djokovic |
| collection | DOAJ |
| description | Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions. |
| first_indexed | 2024-03-11T16:59:42Z |
| format | Article |
| id | doaj.art-cb91440d501a47c9b09f5930047a0788 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-03-11T16:59:42Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-cb91440d501a47c9b09f5930047a07882023-10-20T11:49:09ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-10-011010.3389/fcvm.2023.12604781260478Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombusAleksandra Djokovic0Aleksandra Djokovic1Gordana Krljanac2Gordana Krljanac3Predrag Matic4Predrag Matic5Rastko Zivic6Rastko Zivic7Vuk Djulejic8Vuk Djulejic9Marija Marjanovic Haljilji10Dusan Popovic11Dusan Popovic12Branka Filipovic13Branka Filipovic14Svetlana Apostolovic15Svetlana Apostolovic16Faculty of Medicine, University of Belgrade, Belgrade, SerbiaDepartment of Cardiology, University Hospital Center Bezanijska Kosa, Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaCardiology Clinic, University Clinical Center of Serbia, Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaClinic for Vascular Surgery, Institute for Cardiovascular Diseases “Dedinje”, Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaDepartment for Surgery, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaFaculty of Medicine, Institute of Anatomy, Belgrade, SerbiaDepartment for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaDepartment for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbiaFaculty of Medicine, University of Belgrade, Belgrade, SerbiaDepartment for Gastroenterology, Clinical Hospital Center Dr Dragisa Misovic “Dedinje”, BelgradeSerbiaCoronary Care Unit, Cardiology Clinic, University Clinical Center of Nis, Nis, SerbiaFaculty of Medicine, University of Nis, Nis, SerbiaSpontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1260478/fullspontaneous coronary artery dissectionacute coronary syndromepathophysiologywomen’s healthpregnancyfibromuscular dysplasia |
| spellingShingle | Aleksandra Djokovic Aleksandra Djokovic Gordana Krljanac Gordana Krljanac Predrag Matic Predrag Matic Rastko Zivic Rastko Zivic Vuk Djulejic Vuk Djulejic Marija Marjanovic Haljilji Dusan Popovic Dusan Popovic Branka Filipovic Branka Filipovic Svetlana Apostolovic Svetlana Apostolovic Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus Frontiers in Cardiovascular Medicine spontaneous coronary artery dissection acute coronary syndrome pathophysiology women’s health pregnancy fibromuscular dysplasia |
| title | Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus |
| title_full | Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus |
| title_fullStr | Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus |
| title_full_unstemmed | Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus |
| title_short | Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus |
| title_sort | pathophysiology of spontaneous coronary artery dissection hematoma not thrombus |
| topic | spontaneous coronary artery dissection acute coronary syndrome pathophysiology women’s health pregnancy fibromuscular dysplasia |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1260478/full |
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