Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility
Abstract Background Streptococcus suis is a major cause of meningitis, arthritis, and pneumonia in pigs worldwide, and an emerging pathogen in humans. In Sweden, S. suis has previously received little attention but has in recent years become increasingly recognized as affecting the pig production. T...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-06-01
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| Series: | Acta Veterinaria Scandinavica |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13028-020-00533-3 |
| _version_ | 1818854210679078912 |
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| author | Anna Werinder Anna Aspán Annette Backhans Marie Sjölund Bengt Guss Magdalena Jacobson |
| author_facet | Anna Werinder Anna Aspán Annette Backhans Marie Sjölund Bengt Guss Magdalena Jacobson |
| author_sort | Anna Werinder |
| collection | DOAJ |
| description | Abstract Background Streptococcus suis is a major cause of meningitis, arthritis, and pneumonia in pigs worldwide, and an emerging pathogen in humans. In Sweden, S. suis has previously received little attention but has in recent years become increasingly recognized as affecting the pig production. The aim of the present study was to investigate the occurrence, serotypes and antimicrobial susceptibility of S. suis in Swedish grower pigs from herds with and without reported S. suis associated disease, as well as possible associations between S. suis associated disease and selected environmental and production factors. Swab samples were taken from the tonsils of clinically healthy 8–13-week-old grower pigs from ten case herds and ten control herds. Isolates were cultured, identified using MALDI–TOF MS, and serotyped using latex agglutination. The antimicrobial susceptibility of 188 isolates was tested using broth microdilution. Production data was gathered and environmental parameters were measured on the farms. Results Streptococcus suis was isolated from 95% of the sampled pigs in both the case and the control herds. Serotypes 3, 4, 5, 7, 9, 10, 11, 15, 16, and 17–34 were detected, although a majority of the isolates (81.5%) were non-typeable. There was less diversity among the serotypes isolated from the case herds than among those from the control herds; four and nine different serotypes, respectively. Isolates resistant to penicillin (3.8%) were reported for the first time in Sweden. Tetracycline resistance was common (88.4%). No association was noted between the production and the environmental factors investigated, and the carriership of S. suis. Conclusions The carriership of S. suis was found to be higher in clinically healthy Swedish pigs than previously estimated, and for the first time, the presence of Swedish isolates resistant to penicillin was reported. Many of the most commonly disease-associated serotypes, e.g. serotypes 2, 9, 3, and 7, were detected in healthy grower pigs although further studies are needed to investigate the virulence of these isolates. |
| first_indexed | 2024-12-19T07:49:05Z |
| format | Article |
| id | doaj.art-cb93fb33aa1645d3a7a7da9171317948 |
| institution | Directory Open Access Journal |
| issn | 1751-0147 |
| language | English |
| last_indexed | 2024-12-19T07:49:05Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Veterinaria Scandinavica |
| spelling | doaj.art-cb93fb33aa1645d3a7a7da91713179482022-12-21T20:30:15ZengBMCActa Veterinaria Scandinavica1751-01472020-06-016211910.1186/s13028-020-00533-3Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibilityAnna Werinder0Anna Aspán1Annette Backhans2Marie Sjölund3Bengt Guss4Magdalena Jacobson5Department of Clinical Sciences, Swedish University of Agricultural Sciences (SLU)Department of Microbiology, National Veterinary Institute (SVA)Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute (SVA)Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute (SVA)Department of Biomedical Science and Veterinary Public Health, Swedish University of Agricultural Sciences (SLU)Department of Clinical Sciences, Swedish University of Agricultural Sciences (SLU)Abstract Background Streptococcus suis is a major cause of meningitis, arthritis, and pneumonia in pigs worldwide, and an emerging pathogen in humans. In Sweden, S. suis has previously received little attention but has in recent years become increasingly recognized as affecting the pig production. The aim of the present study was to investigate the occurrence, serotypes and antimicrobial susceptibility of S. suis in Swedish grower pigs from herds with and without reported S. suis associated disease, as well as possible associations between S. suis associated disease and selected environmental and production factors. Swab samples were taken from the tonsils of clinically healthy 8–13-week-old grower pigs from ten case herds and ten control herds. Isolates were cultured, identified using MALDI–TOF MS, and serotyped using latex agglutination. The antimicrobial susceptibility of 188 isolates was tested using broth microdilution. Production data was gathered and environmental parameters were measured on the farms. Results Streptococcus suis was isolated from 95% of the sampled pigs in both the case and the control herds. Serotypes 3, 4, 5, 7, 9, 10, 11, 15, 16, and 17–34 were detected, although a majority of the isolates (81.5%) were non-typeable. There was less diversity among the serotypes isolated from the case herds than among those from the control herds; four and nine different serotypes, respectively. Isolates resistant to penicillin (3.8%) were reported for the first time in Sweden. Tetracycline resistance was common (88.4%). No association was noted between the production and the environmental factors investigated, and the carriership of S. suis. Conclusions The carriership of S. suis was found to be higher in clinically healthy Swedish pigs than previously estimated, and for the first time, the presence of Swedish isolates resistant to penicillin was reported. Many of the most commonly disease-associated serotypes, e.g. serotypes 2, 9, 3, and 7, were detected in healthy grower pigs although further studies are needed to investigate the virulence of these isolates.http://link.springer.com/article/10.1186/s13028-020-00533-3Antibiotic resistanceBacteriaEnvironmental factorsInfectious diseasesMeningitisMicrobiology |
| spellingShingle | Anna Werinder Anna Aspán Annette Backhans Marie Sjölund Bengt Guss Magdalena Jacobson Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility Acta Veterinaria Scandinavica Antibiotic resistance Bacteria Environmental factors Infectious diseases Meningitis Microbiology |
| title | Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility |
| title_full | Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility |
| title_fullStr | Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility |
| title_full_unstemmed | Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility |
| title_short | Streptococcus suis in Swedish grower pigs: occurrence, serotypes, and antimicrobial susceptibility |
| title_sort | streptococcus suis in swedish grower pigs occurrence serotypes and antimicrobial susceptibility |
| topic | Antibiotic resistance Bacteria Environmental factors Infectious diseases Meningitis Microbiology |
| url | http://link.springer.com/article/10.1186/s13028-020-00533-3 |
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